Fluorescence polarization assays for chemical contaminants in food and environmental analyses

H Zhang, S Yang, K De Ruyck, NV Beloglazova… - TrAC Trends in …, 2019 - Elsevier
Fluorescence polarization (FP) assays play an important role in the detection of chemical
contaminants in food and environmental due to a number of key advantages since last …

Fluorescence anisotropy (polarization): from drug screening to precision medicine

H Zhang, Q Wu, MY Berezin - Expert opinion on drug discovery, 2015 - Taylor & Francis
Introduction: Fluorescence anisotropy (FA) is one of the major established methods
accepted by industry and regulatory agencies for understanding the mechanisms of drug …

Improving Paclitaxel Delivery: In Vitro and In Vivo Characterization of PEGylated Polyphosphoester-Based Nanocarriers

F Zhang, S Zhang, SF Pollack, R Li… - Journal of the …, 2015 - ACS Publications
Nanomaterials have great potential to offer effective treatment against devastating diseases
by providing sustained release of high concentrations of therapeutic agents locally …

Nanothermometry: from microscopy to thermal treatments

H Zhou, M Sharma, O Berezin, D Zuckerman… - …, 2016 - Wiley Online Library
Measuring temperature in cells and tissues remotely, with sufficient sensitivity, and in real
time presents a new paradigm in engineering, chemistry and biology. Traditional sensors …

Minimization of self‐quenching fluorescence on dyes conjugated to biomolecules with multiple labeling sites via asymmetrically charged NIR fluorophores

NG Zhegalova, S He, H Zhou, DM Kim… - Contrast media & …, 2014 - Wiley Online Library
Self‐aggregation of dyes even at low concentrations poses a considerable challenge in
preparing sufficiently bright molecular probes for in vivo imaging, particularly in the …

Spectrally resolved fluorescence lifetime imaging of Nile red for measurements of intracellular polarity

JA Levitt, PH Chung, K Suhling - Journal of biomedical optics, 2015 - spiedigitallibrary.org
Spectrally resolved confocal microscopy and fluorescence lifetime imaging have been used
to measure the polarity of lipid-rich regions in living HeLa cells stained with Nile red. The …

Symmetry-breaking in cationic polymethine dyes: part 2. Shape of electronic absorption bands explained by the thermal fluctuations of the solvent reaction field

AE Masunov, D Anderson, AY Freidzon… - The Journal of …, 2015 - ACS Publications
The electronic absorption spectra of the symmetric cyanines exhibit dramatic dependence
on the conjugated chain length: whereas short-chain homologues are characterized by the …

PEGylated peptide to TIP1 is a novel targeting agent that binds specifically to various cancers in vivo

V Kapoor, AK Singh, BE Rogers, D Thotala… - Journal of Controlled …, 2019 - Elsevier
Targeted molecular imaging allows specific visualization and monitoring of tumors. Cancer-
specific peptides have been developed for imaging and therapy. Peptides that specifically …

Holistic assessment of covalently labeled core–shell polymeric nanoparticles with fluorescent contrast agents for theranostic applications

TP Gustafson, YH Lim, JA Flores, GS Heo, F Zhang… - Langmuir, 2014 - ACS Publications
The successful development of degradable polymeric nanostructures as optical probes for
use in nanotheranostic applications requires the intelligent design of materials such that …

Multispectral measurement of contrast in tissue-mimicking phantoms in near-infrared spectral range of 650 to 1600 nm

D Salo, H Zhang, DM Kim… - Journal of biomedical …, 2014 - spiedigitallibrary.org
In order to identify the optimal imaging conditions for the highest spatial contrast in biological
tissue, we explored the properties of a tissue-mimicking phantom as a function of the …