In mammals, male gametes are produced inside the testis by spermatogenesis, which has
three phases: mitotic proliferation of spermatogonia, meiosis of spermatocytes, and haploid …

MicroRNAs (miRNAs) are transcriptional and posttranscriptional regulators involved in
nearly all known biological processes in distant eukaryotic clades. Their discovery and …

MicroRNAs, or miRNAs, post-transcriptionally repress the expression of protein-coding
genes. The human genome encodes over 1000 miRNA genes that collectively target the …

Epididymosomes are small membrane vesicles that are secreted by epididymal epithelial
cells and are involved in posttesticular sperm maturation. Although their role in protein …

In the analysis of biological systems, it is of interest to identify the components of the system
and to monitor their changes in abundance under different conditions. The AQUA …

The Sertoli cells are critical regulators of testis differentiation and development. In the adult,
however, their known function is restricted largely to maintenance of spermatogenesis. To …

MicroRNAs applications were vastly studied throughout the years, spanning from potential
cancer biomarkers to targeted therapies for various diseases. Out of these utilizations, this …

Endothelial functions are highly regulated by imposed shear stress in vivo. The
characteristics of shear stress determine mechanotransduction events that regulate …

Background The RNase III endonuclease Dicer is an important regulator of gene expression
that processes microRNAs (miRNAs) and small interfering RNAs (siRNAs). The best …

The epididymis is responsible for post-testicular sperm maturation, which consists in the
acquisition of forward motility and fertilizing ability. This organ is composed of three main …