Effects of excess PTH on nonclassical target organs

S Bro, K Olgaard - American journal of kidney diseases, 1997 - Elsevier
The classical target organs for parathyroid hormone (PTH) are the bone and kidneys. In
uremia, however, numerous studies have shown that PTH may also affect the function of a …

Benefits of calcitriol therapy and serum phosphorus control in dogs and cats with chronic renal failure: both are essential to prevent or suppress toxic …

LA Nagode, DJ Chew, M Podell - … Clinics of North America: Small Animal …, 1996 - Elsevier
Benefits of calcitriol therapy in uremic dogs and cats are considered by discussing
mechanisms underlying the positive responses to a survey relating to this treatment. The …

Central nervous dysfunction in uremia

MJ Smogorzewski - American journal of kidney diseases, 2001 - Elsevier
The mechanisms of central nervous system dysfunction in uremia are multifactorial and only
partially characterized. Studies using sealed presynaptic nerve terminals (synaptosomes) for …

Chronic renal failure is a state of cellular calcium toxicity

SG Massry, GZ Fadda - American journal of kidney diseases, 1993 - Elsevier
Studies on the metabolic profile of many cells have shown that chronic renal failure (CRF) is
associated with a significant elevation in the basal levels of cytosolic calcium ([Ca 2+] i). This …

Experimental uremia affects hypothalamic amino acid neurotransmitter milieu

F Schaefer, M Vogel, G Kerkhoff, J Woitzik… - Journal of the …, 2001 - journals.lww.com
Chronic renal failure is associated with delayed puberty and hypogonadism. To investigate
the mechanisms subserving the reported reduced pulsatile release of gonadotropin …

Verapamil reverses abnormal [Ca2+] i and carbohydrate metabolism of PMNL of dialysis patients

WH Hörl, M Haag-Weber, B Mai, SG Massry - Kidney international, 1995 - Elsevier
Verapamil reverses abnormal [Ca 2+] i and carbohydrate metabolism of PMNL of dialyis
patients. The basal levels of cytosolic calcium ([Ca 2+] i) of polymorphonuclear leukocytes …

Verapamil prevents chronic renal failure-induced abnormalities in lipid metabolism

M Akmal, S Perkins, SE Kasim, HY Oh… - American journal of …, 1993 - Elsevier
Hypertriglyceridemia is common in chronic renal failure (CRF); this derangement is due to
decreased peripheral removal of triglycerides. Certain data indicate that the state of …

Elevated myocardial cytosolic calcium impairs insulin-like growth factor-1-stimulated protein synthesis in chronic renal failure

DP QING, HU Ding, JAY VADGAMA… - Journal of the …, 1999 - journals.lww.com
Rats and humans with chronic renal failure (CRF) are reported to have resistance to
recombinant human insulin-like growth factor-1 (rhIGF-1). Because basal cytosolic calcium …

Neuropsychiatric consequences of renal failure

TM Brown, RLS Brown - Psychosomatics, 1995 - Elsevier
Neuropsychiatric Consequences of Renal Failure Page 1 Review Article Neuropsychiatric
Consequences of Renal Failure THOMAS M. BROWN, CAPT, USAF, MC REBEKAH LS …

Reduced activity of Na (+)-K+ ATPase of pancreatic islets in chronic renal failure: role of secondary hyperparathyroidism.

SM Hajjar, GZ Fadda, P Thanakitcharu… - Journal of the …, 1992 - journals.lww.com
Abstract The activity of Na (+)-K+ ATPase of pancreatic islets modulates their insulin
secretion. The study presented here examined the activity of this enzyme in pancreatic islets …