Antimicrobial peptides–Advances in development of therapeutic applications
The severe infection is becoming a significant health problem which threaten the lives of
patients and the safety and economy of society. In the way of finding new strategy …
patients and the safety and economy of society. In the way of finding new strategy …
[HTML][HTML] Advances in development of antimicrobial peptidomimetics as potential drugs
The rapid emergence of multidrug-resistant pathogens has evolved into a global health
problem as current treatment options are failing for infections caused by pan-resistant …
problem as current treatment options are failing for infections caused by pan-resistant …
[HTML][HTML] Correlation between hemolytic activity, cytotoxicity and systemic in vivo toxicity of synthetic antimicrobial peptides
I Greco, N Molchanova, E Holmedal, H Jenssen… - Scientific reports, 2020 - nature.com
The use of non-standard toxicity models is a hurdle in the early development of antimicrobial
peptides towards clinical applications. Herein we report an extensive in vitro and in vivo …
peptides towards clinical applications. Herein we report an extensive in vitro and in vivo …
[HTML][HTML] Halogenation as a tool to tune antimicrobial activity of peptoids
N Molchanova, JE Nielsen, KB Sørensen… - Scientific reports, 2020 - nature.com
Antimicrobial peptides have attracted considerable interest as potential new class of
antibiotics against multi-drug resistant bacteria. However, their therapeutic potential is …
antibiotics against multi-drug resistant bacteria. However, their therapeutic potential is …
[HTML][HTML] Exploring the role of unnatural amino acids in antimicrobial peptides
Cationic antimicrobial peptides (CAMPs) are a promising alternative to treat multidrug-
resistant bacteria, which have developed resistance to all the commonly used antimicrobial …
resistant bacteria, which have developed resistance to all the commonly used antimicrobial …
[HTML][HTML] Natural and synthetic halogenated amino acids—Structural and bioactive features in antimicrobial peptides and peptidomimetics
The 3D structure and surface characteristics of proteins and peptides are crucial for
interactions with receptors or ligands and can be modified to some extent to modulate their …
interactions with receptors or ligands and can be modified to some extent to modulate their …
Recent advances in the development of anti-infective peptoids
In the search for new sources of antimicrobials many researchers have investigated
antimicrobial peptides (AMPs) as templates for the design of innovative therapeutics …
antimicrobial peptides (AMPs) as templates for the design of innovative therapeutics …
[HTML][HTML] Antimicrobial peptide mimics for clinical use: does size matter?
The search for efficient antimicrobial therapies that can alleviate suffering caused by
infections from resistant bacteria is more urgent than ever before. Infections caused by multi …
infections from resistant bacteria is more urgent than ever before. Infections caused by multi …
[HTML][HTML] Antimicrobial peptides against bacterial pathogens: Innovative delivery nanosystems for pharmaceutical applications
E Imperlini, F Massaro, F Buonocore - Antibiotics, 2023 - mdpi.com
The introduction of antibiotics has revolutionized the treatment and prevention of microbial
infections. However, the global spread of pathogens resistant to available antibiotics is a …
infections. However, the global spread of pathogens resistant to available antibiotics is a …
[HTML][HTML] S100 proteins as novel therapeutic targets in psoriasis and other autoimmune diseases
Psoriasis is one of the most common inflammatory skin diseases affecting about 1–3% of the
population. One of the characteristic abnormalities in psoriasis is the excessive production of …
population. One of the characteristic abnormalities in psoriasis is the excessive production of …