Pancreatectomy, islet cell transplantation, and nutrition considerations
S Narayanan, N Bhutiani, DT Adamson… - Nutrition in Clinical …, 2021 - Wiley Online Library
Pancreatic islet transplantation is a reliable approach for treating insulin‐deficient diabetes.
This established β‐cell replacement approach has shown considerable improvements in the …
This established β‐cell replacement approach has shown considerable improvements in the …
Surgical approach and short-term outcomes in adults and children undergoing total pancreatectomy with islet autotransplantation: A report from the Prospective …
Background Total pancreatectomy with islet autotransplantation (TPIAT) is a viable option for
treating debilitating recurrent acute pancreatitis (RAP) and chronic pancreatitis (CP) in …
treating debilitating recurrent acute pancreatitis (RAP) and chronic pancreatitis (CP) in …
Human pancreatic tissue dissociation enzymes for islet isolation: Advances and clinical perspectives
G Loganathan, AN Balamurugan… - Diabetes & Metabolic …, 2020 - Elsevier
Background and aims Successful clinical human allo or auto-islet transplantation requires
the recovery of a sufficient number of functional islets from either brain-dead or chronic …
the recovery of a sufficient number of functional islets from either brain-dead or chronic …
Donor age significantly influences the Raman spectroscopic biomolecular fingerprint of human pancreatic extracellular matrix proteins following collagenase-based …
RM Spiers, J Marzi, EM Brauchle, SE Cross… - Acta biomaterialia, 2019 - Elsevier
Despite the enormous advances in the field of clinical pancreatic islet transplantation over
the past two decades, the human islet isolation procedure remains suboptimal. Islets are …
the past two decades, the human islet isolation procedure remains suboptimal. Islets are …
Pancreatic stellate cells prolong ex vivo islet viability and function and improve engraftment
Preserving islet health and function is critical during pretransplant culture to improve islet
transplantation outcome and for ex vivo modeling of diabetes for pharmaceutical drug …
transplantation outcome and for ex vivo modeling of diabetes for pharmaceutical drug …
A scalable human islet 3D-culture platform maintains cell mass and function long-term for transplantation
K Omori, M Qi, M Salgado, N Gonzalez, LT Hui… - American Journal of …, 2024 - Elsevier
Present-day islet culture methods provide short-term maintenance of cell viability and
function, limiting access to islet transplantation. Attempts to lengthen culture intervals remain …
function, limiting access to islet transplantation. Attempts to lengthen culture intervals remain …
Progress in individualizing autologous islet isolation techniques for pediatric islet autotransplantation after total pancreatectomy in children for chronic pancreatitis
JJ Wilhelm, AN Balamurugan, MD Bellin… - American Journal of …, 2021 - Wiley Online Library
Total pancreatectomy with islet autotransplantation is performed to treat chronic pancreatitis
in children. Successful islet isolation must address the challenges of severe pancreatic …
in children. Successful islet isolation must address the challenges of severe pancreatic …
[PDF][PDF] 胶原酶研究进展与应用
宋易航， 王楚浩， 方柏山 - 化工学报, 2019 - core.ac.uk
胶原蛋白广泛存在于有机体生命各组织, 是构成生命体的基础性蛋白之一.
胶原蛋白结构相对复杂, 稳定性良好, 不易受到普通蛋白酶的降解破坏. 而基质金属蛋白酶和 …
胶原蛋白结构相对复杂, 稳定性良好, 不易受到普通蛋白酶的降解破坏. 而基质金属蛋白酶和 …
Allogeneic islet isolation: Methods to improve islet cell transplantation with new technologies in organ transplant retrieval and isolation techniques
AN Balamurugan, KK Samaga, S Narayanan… - Pancreas and Beta Cell …, 2022 - Elsevier
Islet cell transplantation (IT) is a proven therapy in preventing severe hypoglycemia and
restoring insulin independence for the subgroups of patients with type 1 diabetes and …
restoring insulin independence for the subgroups of patients with type 1 diabetes and …
Ductal cell reprograming to insulin-producing cells as a potential beta cell replacement source for islet auto-transplant recipients
Islet cell autotransplantation is a new and promising therapy for maintaining blood glucose
levels and improving the quality of life in patients with chronic pancreatitis (CP). Though this …
levels and improving the quality of life in patients with chronic pancreatitis (CP). Though this …