The relationship between high body weight and mental health has been studied for several
decades. Improvements in the quality of epidemiological, mechanistic and psychological …

Populations with common physical diseases–such as cardiovascular diseases, cancer and
neurodegenerative disorders–experience substantially higher rates of major depressive …

Growing evidence suggests that relative carbohydrate intake affects depression; however,
the association between carbohydrates and depression remains controversial. To test this …

Most genome-wide association studies (GWAS) of major depression (MD) have been
conducted in samples of European ancestry. Here we report a multi-ancestry GWAS of MD …

Background Depression is frequently accompanied by other mental disorders and various
somatic diseases; however, previous comorbidity studies often relied on self-reported data …

Objective: Evidence from anti-inflammatory drug trials for the treatment of depression has
been inconsistent. This may be ascribed to the differing symptom-specific effects of …

Objectives Obesity is associated with increased risk of depression, but the extent to which
this association is symptom-specific is unknown. We examined the associations of …

Background Observational studies have indicated that depression is associated with
coronary artery disease (CAD) and myocardial infarction. Nevertheless, causal associations …

In the absence of obesity, adverse lifestyle behaviours, and use of medication such as
opioids serum testosterone concentrations decrease by only a minimal amount at least until …

Background There is increasing attention on the association of socioeconomic status and
individual behaviors (SES/IB) with mental health. However, the impacts of SES/IB on mental …