Poly (N-isopropylacrylamide)-based thermoresponsive surfaces provide new types of biomedical applications

K Nagase, M Yamato, H Kanazawa, T Okano - Biomaterials, 2018 - Elsevier
Thermoresponsive surfaces, prepared by grafting of poly (N-isopropylacrylamide)(PIPAAm)
or its copolymers, have been investigated for biomedical applications. Thermoresponsive …

Engineering microscale topographies to control the cell–substrate interface

M Nikkhah, F Edalat, S Manoucheri, A Khademhosseini - Biomaterials, 2012 - Elsevier
Cells in their in vivo microenvironment constantly encounter and respond to a multitude of
signals. While the role of biochemical signals has long been appreciated, the importance of …

Scaffolding in tissue engineering: general approaches and tissue-specific considerations

BP Chan, KW Leong - European spine journal, 2008 - Springer
Scaffolds represent important components for tissue engineering. However, researchers
often encounter an enormous variety of choices when selecting scaffolds for tissue …

Biomimetic scaffolds for tissue engineering

TG Kim, H Shin, DW Lim - Advanced Functional Materials, 2012 - Wiley Online Library
Biomimetic scaffolds mimic important features of the extracellular matrix (ECM) architecture
and can be finely controlled at the nano‐or microscale for tissue engineering. Rational …

Nanotopography-guided tissue engineering and regenerative medicine

HN Kim, A Jiao, NS Hwang, MS Kim, DH Kim… - Advanced drug delivery …, 2013 - Elsevier
Human tissues are intricate ensembles of multiple cell types embedded in complex and well-
defined structures of the extracellular matrix (ECM). The organization of ECM is frequently …

Thermoresponsive interfaces obtained using poly (N-isopropylacrylamide)-based copolymer for bioseparation and tissue engineering applications

K Nagase - Advances in Colloid and Interface Science, 2021 - Elsevier
Abstract Poly (N-isopropylacrylamide)(PNIPAAm) is the most well-known and widely used
stimuli-responsive polymer in the biomedical field owing to its ability to undergo temperature …

Stimuli-responsive interfaces and systems for the control of protein–surface and cell–surface interactions

MA Cole, NH Voelcker, H Thissen, HJ Griesser - Biomaterials, 2009 - Elsevier
Real-time control over and reversibility of biomolecule–surface interactions at interfaces is
an increasingly important goal for a range of scientific fields and applications. The field of …

Controlling cell behavior through the design of polymer surfaces

NM Alves, I Pashkuleva, RL Reis, JF Mano - Small, 2010 - Wiley Online Library
Polymers have gained a remarkable place in the biomedical field as materials for the
fabrication of various devices and for tissue engineering applications. The initial acceptance …

Injectable biomaterials for regenerating complex craniofacial tissues

JD Kretlow, S Young, L Klouda, M Wong… - Advanced …, 2009 - Wiley Online Library
Engineering complex tissues requires a precisely formulated combination of cells,
spatiotemporally released bioactive factors, and a specialized scaffold support system …

Synthesis of photodegradable hydrogels as dynamically tunable cell culture platforms

AM Kloxin, MW Tibbitt, KS Anseth - Nature protocols, 2010 - nature.com
We describe a detailed procedure to create photolabile, polyethylene glycol (PEG)-based
hydrogels and manipulate material properties in situ. The cytocompatible chemistry and …