Programmed cell death (PCD) is the universal process that maintains cellular homeostasis
and regulates all living systems' development, health and disease. Out of all, apoptosis is …

Due to the sustained proliferative potential of cancer cells, inducing cell death is a potential
strategy for cancer therapy. Paraptosis is a mode of cell death characterized by endoplasmic …

Most anticancer treatments trigger tumor cell death through apoptosis, where initiation of
proteolytic action of caspase protein is a basic need. But under certain circumstances …

Cancer cells are disordered by nature and thus featured by higher internal redox level than
healthy cells. Redox imbalance could trigger programmed cell death if exceeded a certain …

Paraptosis is a type of programmed cell death that is characterized by dilation of the
endoplasmic reticulum (ER) and/or mitochondria. Since paraptosis is morphologically and …

Lung cancer is one of the most common malignant tumors and a leading cause of cancer-
related death in the worldwide. Various anticancer drugs, such as cisplatin and pemetrexed …

Swainsonine (SW), an indolizidine alkaloid extracted from locoweeds, was shown toxic
effects in multiple studies, but the underlying action mechanism remains unclear. SW is …

Pachymic acid has various pharmacological effects, including anti‐inflammatory,
antioxidant, immunomodulatory, and antitumor. However, the role of pachymic acid in …

Edible flowers are attracting special therapeutic attention and their administration is on the
rise. Edible flowers play pivotal modulatory roles on oxidative stress and related …

Nature is a rich source of natural drug-like compounds with minimal side effects.
Phytochemicals better known as “Natural Products” are found abundantly in a number of …