[HTML][HTML] The traditional Chinese medicines treat chronic heart failure and their main bioactive constituents and mechanisms

J Chen, X Wei, Q Zhang, Y Wu, G Xia, H Xia… - … Pharmaceutica Sinica B, 2023 - Elsevier
Chronic heart failure (CHF) is a severe public health problem with increasing morbidity and
mortality, any treatment targeting a single session is insufficient to tackle this. CHF is …

[HTML][HTML] Trimetazidine in heart failure

H Shu, Y Peng, W Hang, N Zhou… - Frontiers in …, 2021 - frontiersin.org
Heart failure is a systemic syndrome caused by multiple pathological factors. Current
treatments do not have satisfactory outcomes. Several basic studies have revealed the …

[HTML][HTML] Effects of Shexiang Baoxin pill for coronary microvascular function: A systematic review and meta-analysis

M Wang, Y Shan, W Sun, J Han, H Tong… - Frontiers in …, 2021 - frontiersin.org
Background: The coronary microvascular dysfunction has attracted more and more attention
in recent years, but there is still a lack of effective treatment. Shexiang Baoxin Pill is one of …

Shexiang baoxin pill for acute myocardial infarction: Clinical evidence and molecular mechanism of antioxidative stress

J Guo, Z Qin, Q He, TL Fong, NC Lau… - Oxidative Medicine …, 2021 - Wiley Online Library
Acute myocardial infarction (AMI) has been a preclinical and clinical concern due to high
hospitalization rate and mortality. This study was aimed at evaluating the effectiveness and …

[HTML][HTML] Single-nucleus ribonucleic acid-sequencing and spatial transcriptomics reveal the cardioprotection of Shexiang Baoxin Pill (SBP) in mice with myocardial …

W Lin, X Chen, D Wang, R Lu, C Zhang, Z Niu… - Frontiers in …, 2023 - frontiersin.org
Aim: The Shexiang Baoxin Pill (SBP) has been extensively used to treat cardiovascular
diseases in China for four decades, and its clinical efficacy has been widely approved …

[HTML][HTML] The impact of trimetazidine on cardiac fibrosis, inflammation, and function in ischemic cardiomyopathy patients

NM El-Khodary, AI Ghoneim, AA El-Tayaar… - … drugs and therapy, 2023 - Springer
Background Previous studies have shown that Trimetazidine (TMZ) improves vascular
endothelial function and reduces the inflammatory process progression. However, limited …

Therapeutic effects of Aconiti Lateralis Radix Praeparata combined with Zingiberis Rhizoma on doxorubicin-induced chronic heart failure in rats based on an …

JX Wen, RS Li, J Wang, JJ Hao, WH Qin… - Journal of Pharmacy …, 2020 - academic.oup.com
Objectives This study was aimed to explore the mechanism of Aconiti Lateralis Radix
Praeparata (ALRP) and Zingiberis Rhizoma (ZR) on doxorubicin (DOX)-induced chronic …

[HTML][HTML] The efficacy of trimetazidine in non-ischemic heart failure patients: A meta-analysis of randomized controlled trials

C Zhao, C Jin, X He, M Xiang - Reviews in Cardiovascular Medicine, 2021 - imrpress.com
Trimetazidine has been reported to benefit patients with heart failure (HF) and angina. The
impact of trimetazidine on non-ischemic HF remains unclear. We reviewed clinical trials to …

[HTML][HTML] Cost-effectiveness analysis of Shexiang Baoxin Pill (MUSKARDIA) as the add-on treatment to standard therapy for stable coronary artery disease in China

J Pan, P Ping, W Wang, J Zhou, W Zhu - Plos one, 2024 - journals.plos.org
Background Recent evidence indicates that Shexiang Baoxin Pill (MUSKARDIA), as an add-
on treatment to standard therapy for stable coronary artery disease (CAD), is effective …

Shexiang Baoxin pill attenuates ischemic injury by promoting angiogenesis by activation of aldehyde dehydrogenase 2

J Hu, Y Zhao, Y Wu, K Yang, K Hu… - Journal of …, 2021 - journals.lww.com
Promoting angiogenesis is a critical treatment strategy for ischemic cardiovascular diseases.
Shexiang Baoxin Pill (SBP), a traditional Chinese medicine, has been reported to be …