Addictive behavior associated with alcoholism is characterized by compulsive
preoccupation with obtaining alcohol, loss of control over consumption, and development of …

The endogenous cannabinoid system is an important regulatory system involved in
physiological homeostasis. Endocannabinoid signaling is known to modulate neural …

Despite recent data suggesting that the endocannabinoid transmission is a component of
the brain reward system and plays a role in dependence/withdrawal to different habit …

The purpose of this review is to present animal research models that can be used to screen
and/or repurpose medications for the treatment of alcohol abuse and dependence. The …

Rationale It has been suggested that endocannabinoid mechanisms are involved in the
control of ethanol consumption. Objectives The aims of the present study were (1) to …

The purpose of this review paper is to present evidence that rat animal models of alcoholism
provide an ideal platform for developing and screening medications that target alcohol …

Endocannabinoids are lipid mediators that interact with the same cannabinoid receptors that
recognize Δ9‐tetrahydrocannabinol (THC), the psychoactive constituent of marijuana, to …

Colorectal cancer is an increasingly important cause of death in Western countries.
Endocannabinoids inhibit colorectal carcinoma cell proliferation in vitro. In this paper, we …

The present paper describes the results of recent pharmacological studies implicating the
cannabinoid CB1 receptor in the neural circuitry regulating alcohol consumption and …

Alcohol use disorder represents a significant human health problem that leads to substantial
loss of human life and financial cost to society. Currently available treatment options do not …