The impact of systemic inflammation on Alzheimer's disease pathology

J Xie, L Van Hoecke, RE Vandenbroucke - Frontiers in immunology, 2022 - frontiersin.org
Alzheimer's disease (AD) is a devastating age-related neurodegenerative disorder with an
alarming increasing prevalence. Except for the recently FDA-approved Aducanumab of …

[HTML][HTML] Helicobacter pylori and extragastric diseases: A review

AG Gravina, RM Zagari, C De Musis… - World journal of …, 2018 - ncbi.nlm.nih.gov
Helicobacter pylori (H. pylori) infection is very common and affects approximately half of the
world population. It causes gastric diseases, but some authors have reported an association …

Helicobacter pylori‐derived outer membrane vesicles contribute to Alzheimer's disease pathogenesis via C3‐C3aR signalling

J Xie, L Cools, G Van Imschoot… - Journal of …, 2023 - Wiley Online Library
The gut microbiota represents a diverse and dynamic population of microorganisms that can
influence the health of the host. Increasing evidence supports the role of the gut microbiota …

Bacterial extracellular vesicles: an emerging avenue to tackle diseases

J Xie, F Haesebrouck, L Van Hoecke… - Trends in …, 2023 - cell.com
A growing body of research, especially in recent years, has shown that bacterial
extracellular vesicles (bEVs) are one of the key underlying mechanisms behind the …

Helicobacter pylori infection: Beyond gastric manifestations

MLC Santos, BB de Brito, FAF da Silva… - World journal of …, 2020 - pmc.ncbi.nlm.nih.gov
Helicobacter pylori (H. pylori) is a bacterium that infects more than a half of world's
population. Although it is mainly related to the development of gastroduodenal diseases …

Time to test antibacterial therapy in Alzheimer's disease

F Panza, M Lozupone, V Solfrizzi, M Watling… - Brain, 2019 - academic.oup.com
Alzheimer's disease is associated with cerebral accumulation of amyloid-β peptide and
hyperphosphorylated tau. In the past 28 years, huge efforts have been made in attempting to …

Mechanisms of the Epithelial–Mesenchymal Transition and Tumor Microenvironment in Helicobacter pylori-Induced Gastric Cancer

J Baj, I Korona-Głowniak, A Forma, A Maani, E Sitarz… - Cells, 2020 - mdpi.com
Helicobacter pylori (H. pylori) is one of the most common human pathogens, affecting half of
the world's population. Approximately 20% of the infected patients develop gastric ulcers or …

Gram-negative bacteria and their lipopolysaccharides in Alzheimer's disease: pathologic roles and therapeutic implications

H Kim, S Kim, SJ Shin, YH Park, Y Nam, C Kim… - Translational …, 2021 - Springer
Alzheimer's disease (AD) is the most serious age-related neurodegenerative disease and
causes destructive and irreversible cognitive decline. Failures in the development of …

Association of intestinal disorders with Parkinson's disease and Alzheimer's disease: a systematic review and meta-analysis

P Fu, M Gao, KKL Yung - ACS chemical neuroscience, 2019 - ACS Publications
Parkinson's disease (PD) and Alzheimer's disease (AD) are the most common
neurodegenerative disorders, with an overall global incidence of 40 million. Many studies …

Helicobacter pylori outer membrane vesicles induce astrocyte reactivity through nuclear factor-κappa B activation and cause neuronal damage in vivo in a murine …

E Palacios, L Lobos-González, S Guerrero… - Journal of …, 2023 - Springer
Abstract Background Helicobacter pylori (Hp) infects the stomach of 50% of the world's
population. Importantly, chronic infection by this bacterium correlates with the appearance of …