Retinitis pigmentosa: progress in molecular pathology and biotherapeutical strategies

W Liu, S Liu, P Li, K Yao - International Journal of Molecular Sciences, 2022 - mdpi.com
Retinitis pigmentosa (RP) is genetically heterogeneous retinopathy caused by
photoreceptor cell death and retinal pigment epithelial atrophy that eventually results in …

Regulation of epigenetic homeostasis in uveal melanoma and retinoblastoma

P Chai, R Jia, Y Li, C Zhou, X Gu, L Yang, H Shi… - Progress in retinal and …, 2022 - Elsevier
Uveal melanoma (UM) and retinoblastoma (RB), which cause blindness and even death,
are the most frequently observed primary intraocular malignancies in adults and children …

Identification and validation of autophagy-related genes in diabetic retinopathy

N Wang, L Wei, D Liu, Q Zhang, X Xia, L Ding… - Frontiers in …, 2022 - frontiersin.org
Background Diabetic retinopathy (DR) is one of the most common microvascular
complications of diabetes, which is associated with damage of blood-retinal barrier and …

[HTML][HTML] Metabolomics analysis reveals the effect of copper on autophagy in myocardia of pigs

Q Li, J Liao, C Lei, J Shi, H Zhang, Q Han, J Guo… - Ecotoxicology and …, 2021 - Elsevier
Among different synthetic compounds copper (Cu) is persistently and frequently used as
growth promoter, antibacterial, antifungal and antiparasitic agent and has become common …

Effects of copper on oxidative stress and autophagy in hypothalamus of broilers

J Liao, F Yang, H Chen, W Yu, Q Han, Y Li, L Hu… - Ecotoxicology and …, 2019 - Elsevier
The purpose of this research was to discuss the effects of copper (Cu)-induced toxicity on
oxidative stress and autophagy in hypothalamus of broilers. In this study, 240 one-day-old …

A comparative map of macroautophagy and mitophagy in the vertebrate eye

TG McWilliams, AR Prescott, B Villarejo-Zori, G Ball… - Autophagy, 2019 - Taylor & Francis
Photoreception is pivotal to our experience and perception of the natural world; hence the
eye is of prime importance for most vertebrate animals to sense light. Central to visual health …

The crosstalk among autophagy, apoptosis, and pyroptosis in cardiovascular disease

L Cong, Y Bai, Z Guo - Frontiers in Cardiovascular Medicine, 2022 - frontiersin.org
In recent years, the mechanism of cell death has become a hotspot in research on the
pathogenesis and treatment of cardiovascular disease (CVD). Different cell death modes …

Oxidative stress and autophagy-related changes during retinal degeneration and development

L Trachsel-Moncho, S Benlloch-Navarro… - Cell death & …, 2018 - nature.com
Retinitis pigmentosa (RP) is an inherited retinopathy that leads to photoreceptor loss. RP
has been related to oxidative stress, autophagy, and inflammation. This study aimed to …

Autophagy dysfunction and oxidative stress, two related mechanisms implicated in retinitis pigmentosa

ML Moreno, S Mérida, F Bosch-Morell… - Frontiers in …, 2018 - frontiersin.org
Retinitis pigmentosa (RP) is one of the most common clinical subtypes of retinal
degeneration (RD), and it is a neurodegenerative disease that could cause complete …

Autophagy-mediated neuroprotection induced by octreotide in an ex vivo model of early diabetic retinopathy

R Amato, E Catalani, M Dal Monte, M Cammalleri… - Pharmacological …, 2018 - Elsevier
Neuronal injury plays a major role in diabetic retinopathy (DR). Our hypothesis was that the
balance between neuronal death and survival may depend on a similar equilibrium between …