miRNAs can be found in serum and other body fluids and serve as biomarkers for disease.
More importantly, secreted miRNAs, especially those in extracellular vesicles (EVs) such as …

Atherosclerosis is a chronic inflammatory disorder characterized by the gradual build-up of
plaques within the vessel wall of middle-sized and large arteries. Over the past decades …

Targeting residual cardiovascular risk in primary and secondary prevention, would allow
deployment of novel therapeutic agents, facilitating precision medicine. For example …

Background SARS-CoV-2 induces a spectrum of clinical conditions ranging from
asymptomatic infection to life threatening severe disease. Host microRNAs have been …

Endothelial cells (ECs) are the innermost layer of blood vessels that play important roles in
homeostasis and vascular function. However, recent evidence suggests that the onset of …

Atherosclerosis is a chronic inflammatory disease involved in endothelial dysfunction.
Pyroptosis is a pro-inflammatory form of cell death and plays pivotal roles in atherosclerosis …

Background. Our previous study demonstrated that the expression of miR‐16 was
downregulated in the cell and animal models of atherosclerosis (AS), a main contributor to …

Inflammation is a multifaceted biological and pathophysiological response to injuries,
infections, toxins, and inflammatory mechanisms that plays a central role in the progression …

Objective To investigate the epigenetic footprint of idiopathic inflammatory myopathies (IIM)
through characterization of circulating extracellular vesicles (EVs) and the expression of EV …

It is widely recognized that monocytes-macrophages adopt a wide variety of phenotypes,
influencing the inflammatory activity and demyelination in Multiple Sclerosis (MS). However …