The role of the immune microenvironment in bone, cartilage, and soft tissue regeneration: from mechanism to therapeutic opportunity

Y Xiong, BB Mi, Z Lin, YQ Hu, L Yu, KK Zha… - Military Medical …, 2022 - Springer
Bone, cartilage, and soft tissue regeneration is a complex spatiotemporal process recruiting
a variety of cell types, whose activity and interplay must be precisely mediated for effective …

[HTML][HTML] The role of microRNAs in the osteogenic and chondrogenic differentiation of mesenchymal stem cells and bone pathologies

MR Iaquinta, C Lanzillotti, C Mazziotta, I Bononi… - Theranostics, 2021 - ncbi.nlm.nih.gov
Mesenchymal stem cells (MSCs) have been identified in many adult tissues. MSCs can
regenerate through cell division or differentiate into adipocytes, osteoblasts and …

[HTML][HTML] Mesoporous bioactive glasses for regenerative medicine

M Vallet-Regi, AJ Salinas - Materials Today Bio, 2021 - Elsevier
Stem cells are the central element of regenerative medicine (RM). However, in many clinical
applications, the use of scaffolds fabricated with biomaterials is required. In this sense …

Advanced biomaterials and techniques for oral tissue engineering and regeneration—a review

A Matichescu, LC Ardelean, LC Rusu, D Craciun… - Materials, 2020 - mdpi.com
The reconstruction or repair of oral and maxillofacial functionalities and aesthetics is a
priority for patients affected by tooth loss, congenital defects, trauma deformities, or various …

Long non-coding RNAs and microRNAs interplay in osteogenic differentiation of mesenchymal stem cells

C Lanzillotti, M De Mattei, C Mazziotta… - Frontiers in Cell and …, 2021 - frontiersin.org
Long non-coding RNAs (lncRNAs) have gained great attention as epigenetic regulators of
gene expression in many tissues. Increasing evidence indicates that lncRNAs, together with …

Bioactive materials for soft tissue repair

E Mazzoni, MR Iaquinta, C Lanzillotti… - … in bioengineering and …, 2021 - frontiersin.org
Over the past decades, age-related pathologies have increased abreast the aging
population worldwide. The increased age of the population indicates that new tools, such as …

Neuro–bone tissue engineering: emerging mechanisms, potential strategies, and current challenges

W Sun, B Ye, S Chen, L Zeng, H Lu, Y Wan, Q Gao… - Bone Research, 2023 - nature.com
The skeleton is a highly innervated organ in which nerve fibers interact with various skeletal
cells. Peripheral nerve endings release neurogenic factors and sense skeletal signals …

Stem cell-friendly scaffold biomaterials: applications for bone tissue engineering and regenerative medicine

Y Zhang, D Wu, X Zhao, M Pakvasa… - … in bioengineering and …, 2020 - frontiersin.org
Bone is a dynamic organ with high regenerative potential and provides essential biological
functions in the body, such as providing body mobility and protection of internal organs …

Adipogenesis, osteogenesis, and chondrogenesis of human mesenchymal stem/stromal cells: a comparative transcriptome approach

AW Robert, BH Marcon, B Dallagiovanna… - Frontiers in cell and …, 2020 - frontiersin.org
Adipogenesis, osteogenesis and chondrogenesis of human mesenchymal stem/stromal
cells (MSC) are complex and highly regulated processes. Over the years, several studies …

Criteria, challenges, and opportunities for acellularized allogeneic/xenogeneic bone grafts in bone repairing

M Sharifi, R Kheradmandi, M Salehi… - ACS Biomaterials …, 2022 - ACS Publications
As bone grafts become more commonly needed by patients and as donors become scarcer,
acellularized bone grafts (ABGs) are becoming more popular for restorative purposes. While …