[HTML][HTML] A brief review of current maturation methods for human induced pluripotent stem cells-derived cardiomyocytes
RE Ahmed, T Anzai, N Chanthra… - Frontiers in cell and …, 2020 - frontiersin.org
Cardiovascular diseases are the leading cause of death worldwide. Therefore, the discovery
of induced pluripotent stem cells (iPSCs) and the subsequent generation of human induced …
of induced pluripotent stem cells (iPSCs) and the subsequent generation of human induced …
Cardiac fibroblasts and mechanosensation in heart development, health and disease
The term 'mechanosensation'describes the capacity of cells to translate mechanical stimuli
into the coordinated regulation of intracellular signals, cellular function, gene expression …
into the coordinated regulation of intracellular signals, cellular function, gene expression …
[HTML][HTML] 3D co-culture of hiPSC-derived cardiomyocytes with cardiac fibroblasts improves tissue-like features of cardiac spheroids
P Beauchamp, CB Jackson, LC Ozhathil… - Frontiers in molecular …, 2020 - frontiersin.org
Purpose: Both cardiomyocytes and cardiac fibroblasts (CF) play essential roles in cardiac
development, function, and remodeling. Properties of 3D co-cultures are incompletely …
development, function, and remodeling. Properties of 3D co-cultures are incompletely …
Conductive biomaterials for cardiac repair: A review
Y Li, L Wei, L Lan, Y Gao, Q Zhang, H Dawit, J Mao… - Acta biomaterialia, 2022 - Elsevier
Myocardial infarction (MI) is one of the fatal diseases in humans. Its incidence is constantly
increasing annually all over the world. The problem is accompanied by the limited …
increasing annually all over the world. The problem is accompanied by the limited …
[HTML][HTML] Milestones and current achievements in development of multifunctional bioscaffolds for medical application
Tissue engineering (TE) is a rapidly growing interdisciplinary field, which aims to restore or
improve lost tissue function. Despite that TE was introduced more than 20 years ago …
improve lost tissue function. Despite that TE was introduced more than 20 years ago …
[HTML][HTML] Fabrication and Biomedical Applications of Heart-on-a-chip
Q Yang, Z Xiao, X Lv, T Zhang, H Liu - International Journal of …, 2021 - ncbi.nlm.nih.gov
Heart diseases have become the main killer threatening human health, and various
methods have been developed to study heart disease. Among them, heart-on-a-chip has …
methods have been developed to study heart disease. Among them, heart-on-a-chip has …
[HTML][HTML] When stiffness matters: mechanosensing in heart development and disease
During embryonic morphogenesis, the heart undergoes a complex series of cellular
phenotypic maturations (eg, transition of myocytes from proliferative to quiescent or …
phenotypic maturations (eg, transition of myocytes from proliferative to quiescent or …
[HTML][HTML] Cells, materials, and fabrication processes for cardiac tissue engineering
P Montero, M Flandes-Iparraguirre… - … in Bioengineering and …, 2020 - frontiersin.org
Cardiovascular disease is the number one killer worldwide, with myocardial infarction (MI)
responsible for approximately 1 in 6 deaths. The lack of endogenous regenerative capacity …
responsible for approximately 1 in 6 deaths. The lack of endogenous regenerative capacity …
Emerging bioelectronic strategies for cardiovascular tissue engineering and implantation
Heart diseases are currently the leading cause of death worldwide. The ability to create
cardiovascular tissue has numerous applications in understanding tissue development …
cardiovascular tissue has numerous applications in understanding tissue development …
Human iPSC-engineered cardiac tissue platform faithfully models important cardiac physiology
WJ de Lange, ET Farrell, CR Kreitzer… - American Journal …, 2021 - journals.physiology.org
Cardiomyocytes derived from human induced pluripotent stem cells (hiPSC-CM) may
provide an important bridge between animal models and the intact human myocardium …
provide an important bridge between animal models and the intact human myocardium …