The polymorphic fungus Candida albicans is a member of the normal human microbiome. In
most individuals, C. albicans resides as a lifelong, harmless commensal. Under certain …

Highlights•Hsp90 is a molecular chaperone that modulates the function of many client
proteins.•Morphogenesis is an important Candida albicans virulence trait.•Hsp90 regulates …

Microbial pathogens use a number of genetic strategies to invade the host and cause
infection. These common themes are found throughout microbial systems. Secretion of …

Like other microorganisms, free-living Candida albicans is mainly present in a three-
dimensional multicellular structure, which is called a biofilm, rather than in a planktonic form …

Biofilm formation is an important virulence factor for pathogenic fungi. Both yeasts and
filamentous fungi can adhere to biotic and abiotic surfaces, developing into highly organized …

Candida albicans is an opportunistic fungal pathogen that is found in the normal
gastrointestinal flora of most healthy humans. However, under certain environmental …

Fusarium graminearum is an important pathogen of small grains and maize in many areas of
the world. Infected grains are often contaminated with mycotoxins harmful to humans and …

Fungal pathogens exploit diverse mechanisms to survive exposure to antifungal drugs. This
poses concern given the limited number of clinically useful antifungals and the growing …

Only few Candida species, eg, Candida albicans, Candida glabrata, Candida dubliniensis,
and Candida parapsilosis, are successful colonizers of a human host. Under certain …

In eukaryotic cells, a family of serine/threonine protein kinases known as mitogen-activated
protein (MAP) kinases (MAPKs) is involved in the transduction of a variety of extracellular …