Trends in the design and use of elastin-like recombinamers as biomaterials

A Ibáñez-Fonseca, T Flora, S Acosta… - Matrix Biology, 2019 - Elsevier
Abstract Elastin-like recombinamers (ELRs), which derive from one of the repetitive domains
found in natural elastin, have been intensively studied in the last few years from several …

Polypeptide-based systems: From synthesis to application in drug delivery

M Stepanova, A Nikiforov, T Tennikova… - Pharmaceutics, 2023 - mdpi.com
Synthetic polypeptides are biocompatible and biodegradable macromolecules whose
composition and architecture can vary over a wide range. Their unique ability to form …

Common ethical considerations of human-induced pluripotent stem cell research

AE Omole, AOJ Fakoya, KC Nnawuba… - Handbook of stem cell …, 2022 - Springer
Abstract In 2006, Shinya Yamanaka generated induced pluripotent stem cells (iPSCs),
which has been the major scientific event of the decade that caught the eye of many …

Non-viral carriers for nucleic acids delivery: Fundamentals and current applications

S Shtykalova, D Deviatkin, S Freund, A Egorova… - Life, 2023 - mdpi.com
Simple Summary Gene therapy is one of the most promising approaches to treating various
inherited and acquired diseases by delivering genetic constructs into the cells and tissues of …

Protein-based nanoparticles for therapeutic nucleic acid delivery

F Eweje, ML Walsh, K Ahmad, V Ibrahim, A Alrefai… - Biomaterials, 2024 - Elsevier
To realize the full potential of emerging nucleic acid therapies, there is a need for effective
delivery agents to transport cargo to cells of interest. Protein materials exhibit several unique …

A concise review on induced pluripotent stem cell-derived cardiomyocytes for personalized regenerative medicine

P Pushp, DES Nogueira, CAV Rodrigues… - Stem cell reviews and …, 2021 - Springer
The induced pluripotent stem cells (iPSCs) are derived from somatic cells by using
reprogramming factors such as Oct4, Sox2, Klf4, and c-Myc (OSKM) or Oct4, Sox2, Nanog …

Molecular prospect of type-2 diabetes: Nanotechnology based diagnostics and therapeutic intervention

RG Kerry, GP Mahapatra, GK Maurya, S Patra… - Reviews in Endocrine …, 2021 - Springer
About ninety percent of all diabetic conditions account for T2D caused due to abnormal
insulin secretion/action or increased hepatic glucose production. Factors that contribute …

[HTML][HTML] The application of elastin-like peptides in cancer, tissue engineering and ocular disease

D Jiang, Y Yang, X Yang, B Wang, W Fan, Y Liu, X Xin… - OpenNano, 2023 - Elsevier
Elastin-like polypeptides (ELPs) are macromolecular biopolymers composed of natural
amino acids. ELPs can be prepared by genetic engineering so that their amino acid …

Application of Induced Pluripotent Stem Cells in Malignant Solid Tumors

R He, Z Weng, Y Liu, B Li, W Wang, W Meng… - Stem Cell Reviews and …, 2023 - Springer
In the past decade, induced pluripotent stem cells (iPSCs) technology has significantly
progressed in studying malignant solid tumors. This technically feasible reprogramming …

Unleashing the potential of natural protein based nanoparticles for the delivery of therapeutic nucleic Acid: A comprehensive review

K Yadav, SPE Gnanakani, KK Sahu, A Dubey… - International Journal of …, 2024 - Elsevier
Nucleic acid-based therapeutics represent a revolutionary approach in treating genetic
disorders, offering unprecedented potential for addressing pathologies at their molecular …