[HTML][HTML] Membrane-type matrix metalloproteases as diverse effectors of cancer progression
SP Turunen, O Tatti-Bugaeva, K Lehti - Biochimica et Biophysica Acta (BBA …, 2017 - Elsevier
Membrane-type matrix metalloproteases (MT-MMP) are pivotal regulators of cell invasion,
growth and survival. Tethered to the cell membranes by a transmembrane domain or GPI …
growth and survival. Tethered to the cell membranes by a transmembrane domain or GPI …
The expanding role of MT1-MMP in cancer progression
AM Knapinska, GB Fields - Pharmaceuticals, 2019 - mdpi.com
For over 20 years, membrane type 1 matrix metalloproteinase (MT1-MMP) has been
recognized as a key component in cancer progression. Initially, the primary roles assigned …
recognized as a key component in cancer progression. Initially, the primary roles assigned …
Eph-and ephrin-dependent mechanisms in tumor and stem cell dynamics
The erythropoietin-producing hepatocellular (Eph) receptors comprise the largest family of
receptor tyrosine kinases (RTKs). Initially regarded as axon-guidance and tissue-patterning …
receptor tyrosine kinases (RTKs). Initially regarded as axon-guidance and tissue-patterning …
Eicosapentaenoic acid in combination with EPHA2 inhibition shows efficacy in preclinical models of triple-negative breast cancer by disrupting cellular cholesterol …
Triple-negative breast cancer (TNBC), the most aggressive breast cancer subtype, currently
lacks effective targeted therapy options. Eicosapentaenoic acid (EPA), an omega-3 fatty acid …
lacks effective targeted therapy options. Eicosapentaenoic acid (EPA), an omega-3 fatty acid …
In vitro analysis of single chain variable fragment-based immunotoxins against Erythropoietin-producing hepatocellular A2 receptor overexpressed in breast cancer …
A Faraz, J Amani, S Arbabian, SZ Karizi… - Journal of Immunological …, 2024 - Elsevier
Breast cancer is one of the leading causes of cancer deaths worldwide. Thereafter,
designing new treatments with higher specificity and efficacy is urgently required. In this …
designing new treatments with higher specificity and efficacy is urgently required. In this …
Orphan G protein-coupled receptor GPRC5A modulates integrin β 1-mediated epithelial cell adhesion
ABSTRACT G-Protein Coupled Receptor (GPCR), Class C, Group 5, Member A (GPRC5A)
has been implicated in several malignancies. The underlying mechanisms, however, remain …
has been implicated in several malignancies. The underlying mechanisms, however, remain …
EphA2 表达水平与食管鳞癌临床病理特征关系研究
王洪江， 王勇涛， 王兴名 - 中国全科医学, 2015 - chinagp.net
目的分析不同临床病理特征食管鳞癌患者EphA2 表达水平的差异, 探讨血清中EphA2
表达水平对食管鳞癌临床病理特征的评估价值. 方法收集2010-2012 年新疆医科大学附属肿瘤 …
表达水平对食管鳞癌临床病理特征的评估价值. 方法收集2010-2012 年新疆医科大学附属肿瘤 …
[HTML][HTML] Extracellular interactions as key regulators of oncogenic signaling in ovarian cancer and melanoma aggressiveness
J Jukonen - 2024 - helda.helsinki.fi
Growth of metastatic tumors and therapy resistance–often arising in metastatic tumors–are
the main causes of cancer mortalities. Early identification of cases with a potential to …
the main causes of cancer mortalities. Early identification of cases with a potential to …
Magnetic resonance studies of antimicrobial peptides in membranes
The development of microbial resistance to common small molecule antibiotics is continuing
to be a thread to modern medicine and drives the search for novel antibiotics for the clinic …
to be a thread to modern medicine and drives the search for novel antibiotics for the clinic …
Targeting peptides, a Swiss-Army Knife against cancer
V Le Joncour, P Laakkonen - 2017 - books.rsc.org
Characterised by both great selectivity and flexibility, peptides are also considered safe and
usually quite well tolerated by patients. During the past two decades, development of anti …
usually quite well tolerated by patients. During the past two decades, development of anti …