Mesenchymal stem cells and immunomodulation: current status and future prospects

F Gao, SM Chiu, DAL Motan, Z Zhang, L Chen… - Cell death & …, 2016 - nature.com
The unique immunomodulatory properties of mesenchymal stem cells (MSCs) make them
an invaluable cell type for the repair of tissue/organ damage caused by chronic inflammation …

Clinical utility of stem cells for periodontal regeneration

K Hynes, D Menicanin, S Gronthos… - Periodontology …, 2012 - Wiley Online Library
The aim of this review is to discuss the clinical utility of stem cells in periodontal regeneration
by reviewing relevant literature that assesses the periodontal‐regenerative potential of stem …

Mesenchymal stem cell secretes microparticles enriched in pre-microRNAs

TS Chen, RC Lai, MM Lee, ABH Choo… - Nucleic acids …, 2010 - academic.oup.com
Intercellular exchange of protein and RNA-containing microparticles is an increasingly
important mode of cell–cell communication. Here we investigate if mesenchymal stem cells …

iPSC-MSCs with high intrinsic MIRO1 and sensitivity to TNF-α yield efficacious mitochondrial transfer to rescue anthracycline-induced cardiomyopathy

Y Zhang, Z Yu, D Jiang, X Liang, S Liao, Z Zhang… - Stem cell reports, 2016 - cell.com
Mesenchymal stem cells (MSCs) can donate mitochondria and rescue anthracycline-
induced cardiomyocyte (CM) damage, although the underlying mechanisms remain elusive …

A mesoderm-derived precursor for mesenchymal stem and endothelial cells

MA Vodyanik, J Yu, X Zhang, S Tian, R Stewart… - Cell stem cell, 2010 - cell.com
Among the three embryonic germ layers, the mesoderm is a major source of the
mesenchymal precursors giving rise to skeletal and connective tissues, but these precursors …

Enabling a robust scalable manufacturing process for therapeutic exosomes through oncogenic immortalization of human ESC-derived MSCs

TS Chen, F Arslan, Y Yin, SS Tan, RC Lai… - Journal of translational …, 2011 - Springer
Background Exosomes or secreted bi-lipid vesicles from human ESC-derived mesenchymal
stem cells (hESC-MSCs) have been shown to reduce myocardial ischemia/reperfusion …

Resveratrol promotes osteogenesis of human mesenchymal stem cells by upregulating RUNX2 gene expression via the SIRT1/FOXO3A axis

PC Tseng, SM Hou, RJ Chen, HW Peng… - Journal of Bone and …, 2011 - academic.oup.com
Reports of the bone‐protective effects of resveratrol, a naturally occurring phytoestrogen and
agonist for the longevity gene SIRT1, have highlighted this compound as a candidate for …

[HTML][HTML] Modeling familial cancer with induced pluripotent stem cells

DF Lee, J Su, HS Kim, B Chang, D Papatsenko, R Zhao… - Cell, 2015 - cell.com
In vitro modeling of human disease has recently become feasible with induced pluripotent
stem cell (iPSC) technology. Here, we established patient-derived iPSCs from a Li-Fraumeni …

Controlled differentiation of stem cells

NS Hwang, S Varghese, J Elisseeff - Advanced drug delivery reviews, 2008 - Elsevier
The extracellular microenvironment plays a significant role in controlling cellular behavior.
Identification of appropriate biomaterials that support cellular attachment, proliferation and …

Human embryonic mesenchymal stem cell-derived conditioned medium rescues kidney function in rats with established chronic kidney disease

A van Koppen, JA Joles, BWM van Balkom, SK Lim… - PloS one, 2012 - journals.plos.org
Chronic kidney disease (CKD) is a major health care problem, affecting more than 35% of
the elderly population worldwide. New interventions to slow or prevent disease progression …