Recent progress in electrochemical sensors and assays for DNA damage and repair

M Fojta, A Daňhel, L Havran, V Vyskočil - TrAC Trends in Analytical …, 2016 - Elsevier
DNA in cells is permanently exposed to endogenous or exogenous chemical or physical
agents which may cause chemical changes in the DNA structure collectively called “DNA …

An Overview of the Optical and Electrochemical Methods for Detection of DNA--Drug Interactions.

MM Aleksić, V Kapetanović - Acta Chimica Slovenica, 2014 - search.ebscohost.com
A large number of inorganic and organic compounds is able to bind to DNA and form
complexes. Among them, drugs are very important, especially chemotherapeutics. This …

Synthesis, characterization, antimicrobial, density functional theory, and molecular docking studies of novel Mn (II), Fe (III), and Cr (III) complexes incorporating 4-(2 …

HM Abd El-Lateef, MM Khalaf, AA Amer, M Kandeel… - ACS …, 2023 - ACS Publications
This work synthesized three new CrAz2, MnAz2, and FeAz2 complexes and investigated
them using IR, mass, UV spectroscopy, elemental analysis, conductivity and magnetic tests …

A new electrochemical DNA biosensor based on modified carbon paste electrode using graphene quantum dots and ionic liquid for determination of topotecan

H Mahmoudi-Moghaddam, S Tajik, H Beitollahi - Microchemical Journal, 2019 - Elsevier
To study topotecan–DNA interaction and topotecan determination with a modified carbon
paste electrode (CPE), a new electrochemical biosensor is introduced. The biosensor was …

A novel view of the separate and simultaneous binding effects of docetaxel and anastrozole with calf thymus DNA: Experimental and in silico approaches

M Dareini, ZA Tehranizadeh, N Marjani… - … Acta Part A: Molecular …, 2020 - Elsevier
DNA stands as the primary purpose of many anticancer drugs and according to the
performed research on this field, some certain changes contain crucial functionalities in the …

Binding interaction between sorafenib and calf thymus DNA: spectroscopic methodology, viscosity measurement and molecular docking

JH Shi, J Chen, J Wang, YY Zhu - … Acta Part A: Molecular and Biomolecular …, 2015 - Elsevier
The binding interaction of sorafenib with calf thymus DNA (ct-DNA) was studied using UV–
vis absorption spectroscopy, fluorescence emission spectroscopy, circular dichroism (CD) …

Antibacterial, antifungal, anti‐inflammatory evaluation, molecular docking, and density functional theory exploration of 2‐(1H‐benzimidazol‐2‐yl)guanidine mixed …

HM Abd El‐Lateef, MM Khalaf, AA Amer… - Applied …, 2024 - Wiley Online Library
The aim of the present framework is to synthesize and characterize new cobalt (II)(C1),
nickel (II)(C2), and copper (II)(C3) mixed‐ligand complexes incorporating bioactive 8 …

DNA binding studies of antifungal drug posaconazole using spectroscopic and molecular docking methods

SR Madku, BK Sahoo, K Lavanya, RS Reddy… - International Journal of …, 2023 - Elsevier
The binding studies of DNA with small molecules have been an emerging field of research
all the time since DNA as the genetic material is a major biological target for various drugs …

[HTML][HTML] Synthesis, theoretical, spectroscopic and electrochemical DNA binding investigations of 1, 3, 4-thiadiazole derivatives of ibuprofen and ciprofloxacin: Cancer …

SI Farooqi, N Arshad, PA Channar, F Perveen… - … of Photochemistry and …, 2018 - Elsevier
Abstract Two new 1, 3, 4-thiadiazole derivatives of ibuprofen and ciprofloxacin namely {(5-(1-
(4-isobutylphenyl) ethyl)-1, 3, 4-thiadiazol-2-amine)} 1 and {(3-(5-amino-1, 3, 4-thiadiazol-2 …

Investigation of poly (CTAB-MWCNTs) composite based electrochemical DNA biosensor and interaction study with anticancer drug Irinotecan

G Bolat - Microchemical Journal, 2020 - Elsevier
Abstract Development of sensitive, rapid and low-cost DNA detection tools and elucidation
of the structural changes of DNA after interaction with chemotherapeutic drugs is of great …