Osteoporosis is a systemic skeletal disease caused by an imbalance between bone
resorption and formation. Current treatments primarily involve systemic medication and …

O-linked N-acetylglucosamine protein modification (O-GlcNAcylation) is a dynamic post-
translational modification (PTM) involving the covalent binding of serine and/or threonine …

Reactive oxidative species (ROS) generation triggers pyroptosis and induces development
of inflammatory osteolysis. Hecogenin (HG) has anti-inflammatory and antioxidative …

Background: Cadmium (Cd) is a highly toxic and widespread environmental oxidative
stressor that causes a myriad of health problems, including osteoporosis and bone damage …

Glaucoma, as an ischemia-reperfusion (I/R) injury disease, leading irreversible blindness
through the loss of retinal ganglion cells (RGCs), mediated by various pathways. Resveratrol …

Thermal treatment can effectively decontaminate soils but alter their properties. Previous
research mainly focused on volatile organic compounds and metals, ie Hg, neglecting non …

With the improvement of implant design and the expansion of application scenarios,
orthopedic implants have become a common surgical option for treating fractures and end …

Mitochondria exhibit heterogeneous shapes and networks within and among cell types and
tissues, also in normal or osteoporotic bone tissues with complex cell types. This dynamic …

Autophagy plays an important role in determining stem‐cell differentiation. During the
osteogenic differentiation of mesenchymal stem cells (MSCs), autophagosome formation is …

Abstract Selenium (Se) and cadmium (Cd) usually co-existed in soils, especially in areas
with Se-rich soils in China. The potential health consequences for the local populations …