The genetics and epigenetics of atopic dermatitis—filaggrin and other polymorphisms
Y Liang, C Chang, Q Lu - Clinical reviews in allergy & immunology, 2016 - Springer
Atopic dermatitis (AD) is a chronic inflammatory skin disease caused by a combination of
genetic and environmental factors. Genetic evidences depict a complex network comprising …
genetic and environmental factors. Genetic evidences depict a complex network comprising …
Alterations of the microRNA network cause neurodegenerative disease
SS Hébert, B De Strooper - Trends in neurosciences, 2009 - cell.com
Brain development crucially depends on the integrity of microRNA (miRNA) pathways, which
function at the post-transcriptional level as a rheostat of the transcriptome and proteome of …
function at the post-transcriptional level as a rheostat of the transcriptome and proteome of …
The Cambrian conundrum: early divergence and later ecological success in the early history of animals
Diverse bilaterian clades emerged apparently within a few million years during the early
Cambrian, and various environmental, developmental, and ecological causes have been …
Cambrian, and various environmental, developmental, and ecological causes have been …
The genome of a songbird
The zebra finch is an important model organism in several fields, with unique relevance to
human neuroscience,. Like other songbirds, the zebra finch communicates through learned …
human neuroscience,. Like other songbirds, the zebra finch communicates through learned …
The eukaryotic genome as an RNA machine
The past few years have revealed that the genomes of all studied eukaryotes are almost
entirely transcribed, generating an enormous number of non–protein-coding RNAs …
entirely transcribed, generating an enormous number of non–protein-coding RNAs …
The deep evolution of metazoan microRNAs
BM Wheeler, AM Heimberg, VN Moy… - Evolution & …, 2009 - Wiley Online Library
SUMMARY microRNAs (miRNAs) are approximately 22‐nucleotide noncoding RNA
regulatory genes that are key players in cellular differentiation and homeostasis. They might …
regulatory genes that are key players in cellular differentiation and homeostasis. They might …
Micro-RNA abundance and stability in human brain: specific alterations in Alzheimer's disease temporal lobe neocortex
P Sethi, WJ Lukiw - Neuroscience letters, 2009 - Elsevier
Micro-RNA (miRNA) mediated regulation of messenger RNA (mRNA) complexity in the
central nervous system (CNS) is emerging as a critical factor in the control of CNS-specific …
central nervous system (CNS) is emerging as a critical factor in the control of CNS-specific …
MicroRNA control of epithelial–mesenchymal transition and metastasis
The great majority of cancer deaths are due to metastasis, which remains a poorly
understood pathological process. The formation of a metastasis reflects a succession of …
understood pathological process. The formation of a metastasis reflects a succession of …
Systems medicine: the future of medical genomics and healthcare
High-throughput technologies for DNA sequencing and for analyses of transcriptomes,
proteomes and metabolomes have provided the foundations for deciphering the structure …
proteomes and metabolomes have provided the foundations for deciphering the structure …
miRNA malfunction causes spinal motor neuron disease
S Haramati, E Chapnik, Y Sztainberg… - Proceedings of the …, 2010 - National Acad Sciences
Defective RNA metabolism is an emerging mechanism involved in ALS pathogenesis and
possibly in other neurodegenerative disorders. Here, we show that microRNA (miRNA) …
possibly in other neurodegenerative disorders. Here, we show that microRNA (miRNA) …