Quantitative phase imaging (QPI) is a label-free, wide-field microscopy approach with
significant opportunities for biomedical applications. QPI uses the natural phase shift of light …

Simple Summary Senescence is an essential component of tumor cell biology and is a
primary cell stress response to therapy. While the long-term impact of senescence in cancer …

Tumor cells undergo senescence in response to both conventional and targeted cancer
therapies. The induction of senescence in response to cancer therapy can contribute to …

Abstract In 1948, Dennis Gabor proposed the concept of holography, providing a pioneering
solution to a quantitative description of the optical wavefront. After 75 years of development …

In the last decades, the understanding of the complex biological mechanisms that regulate
the life and growth of single cells and their reciprocal interaction has steadily increased. In …

H460 non-small cell lung, HCT116 colon and 4T1 breast tumor cell lines induced into
senescence by exposure to either etoposide or doxorubicin were able to recover …

High throughput drug screening is an established approach to investigate tumor biology and
identify therapeutic leads. Traditional platforms use two-dimensional cultures which do not …

Cytotoxicity quantification of nanoparticles is commonly performed by biochemical assays to
evaluate their biocompatibility and safety. We explored quantitative phase imaging (QPI) …

Prostate cancer (PCa) is one of the leading causes of cancer-related deaths in men.
Although androgen deprivation therapies (ADT) and antiandrogens confer increased …

Identifying drug-resistant cancer cells is of fundamental importance to afford disease and
find the most effective therapies for the patients. Recently, label-free imaging flow cytometry …