Prefrontal cortex, amygdala, and threat processing: implications for PTSD
Posttraumatic stress disorder can be viewed as a disorder of fear dysregulation. An
abundance of research suggests that the prefrontal cortex is central to fear processing—that …
abundance of research suggests that the prefrontal cortex is central to fear processing—that …
A systematic review of neural, cognitive, and clinical studies of anger and aggression
Anger and aggression have large impact on people's safety and the society at large. In order
to provide an intervention to minimise aggressive behaviours, it is important to understand …
to provide an intervention to minimise aggressive behaviours, it is important to understand …
[HTML][HTML] Adolescent anxiety disorders and the developing brain: comparing neuroimaging findings in adolescents and adults
Adolescence is the peak period for the incidence of anxiety disorders. Recent findings have
revealed the immaturity of neural networks underlying emotional regulation in this …
revealed the immaturity of neural networks underlying emotional regulation in this …
Age differences in the neural correlates of anxiety disorders: An fMRI study of response to learned threat
Objective: Although both pediatric and adult patients with anxiety disorders exhibit similar
neural responding to threats, age-related differences have been found in some functional …
neural responding to threats, age-related differences have been found in some functional …
The clinical applications and practical relevance of human conditioning paradigms for posttraumatic stress disorder
DV Zuj, SD Norrholm - Progress in Neuro-Psychopharmacology and …, 2019 - Elsevier
The classical conditioning paradigm of fear learning has spawned a number of experimental
variations for the explanation of posttraumatic stress disorder (PTSD) etiology. These …
variations for the explanation of posttraumatic stress disorder (PTSD) etiology. These …
Safety learning during development: Implications for development of psychopathology
LR Grasser, T Jovanovic - Behavioural Brain Research, 2021 - Elsevier
Fear and safety learning are necessary adaptive behaviors that develop over the course of
maturation. While there is a large body of literature regarding the neurobiology of fear and …
maturation. While there is a large body of literature regarding the neurobiology of fear and …
Early life stress, frontoamygdala connectivity, and biological aging in adolescence: a longitudinal investigation
Early life stress (ELS) may accelerate frontoamygdala development related to
socioemotional processing, serving as a potential source of resilience. Whether this circuit is …
socioemotional processing, serving as a potential source of resilience. Whether this circuit is …
The role of ventromedial and dorsolateral prefrontal cortex in attention and interpretation biases in individuals with general anxiety disorder (GAD): a tDCS study
Background and purpose of the study: Individuals with general anxiety disorder (GAD) have
deficits in emotional and cognitive processing, including cognitive bias, which plays a causal …
deficits in emotional and cognitive processing, including cognitive bias, which plays a causal …
Discrimination exposure, neural reactivity to stress, and psychological distress
DK Grey, JB Purcell, KN Buford… - American Journal of …, 2024 - psychiatryonline.org
Objective: Discrimination exposure has a detrimental impact on mental health, increasing
the risk of depression, anxiety, and posttraumatic stress. The impact discrimination exposure …
the risk of depression, anxiety, and posttraumatic stress. The impact discrimination exposure …
Assessment of conditioned fear extinction in male and female adolescent rats
Pavlovian fear conditioning and extinction have been widely studied across many species to
understand emotional learning and memory. Importantly, it is becoming clear that these …
understand emotional learning and memory. Importantly, it is becoming clear that these …