Analysis of tissue specimens by matrix-assisted laser desorption/ionization imaging mass spectrometry in biological and clinical research

JL Norris, RM Caprioli - Chemical reviews, 2013 - ACS Publications
Human beings are adept at discerning relevant information from complex systems by
processing visual information. Similarly, as scientists labor to understand the fundamental …

MALDI-MSI towards multimodal imaging: challenges and perspectives

M Tuck, F Grélard, L Blanc, N Desbenoit - Frontiers in Chemistry, 2022 - frontiersin.org
Multimodal imaging is a powerful strategy for combining information from multiple images. It
involves several fields in the acquisition, processing and interpretation of images. As …

Using mass spectrometry imaging to map fluxes quantitatively in the tumor ecosystem

M Schwaiger-Haber, E Stancliffe… - Nature …, 2023 - nature.com
Tumors are comprised of a multitude of cell types spanning different microenvironments.
Mass spectrometry imaging (MSI) has the potential to identify metabolic patterns within the …

[PDF][PDF] Lipid zonation and phospholipid remodeling in nonalcoholic fatty liver disease

Z Hall, NJ Bond, T Ashmore, F Sanders, Z Ament… - …, 2017 - Wiley Online Library
Nonalcoholic fatty liver disease (NAFLD) can progress from simple steatosis (ie,
nonalcoholic fatty liver [NAFL]) to nonalcoholic steatohepatitis (NASH), cirrhosis, and cancer …

Inclusive sharing of mass spectrometry imaging data requires a converter for all

AM Race, IB Styles, J Bunch - Journal of proteomics, 2012 - Elsevier
With continued efforts towards a single MSI data format, data conversion routines must be
made universally available. The benefits of a common imaging format, imzML, are slowly …

Applications and continued evolution of glycan imaging mass spectrometry

CT McDowell, X Lu, AS Mehta… - Mass spectrometry …, 2023 - Wiley Online Library
Glycosylation is an important posttranslational modifier of proteins and lipid conjugates
critical for the stability and function of these macromolecules. Particularly important are N …

Use of mass spectrometry for imaging metabolites in plants

YJ Lee, DC Perdian, Z Song, ES Yeung… - The Plant …, 2012 - Wiley Online Library
We discuss and illustrate recent advances that have been made to image the distribution of
metabolites among cells and tissues of plants using different mass spectrometry …

Multimodal imaging based on vibrational spectroscopies and mass spectrometry imaging applied to biological tissue: a multiscale and multiomics review

M Tuck, L Blanc, R Touti, NH Patterson… - Analytical …, 2020 - ACS Publications
Molecular imaging has the potential to unearth important spatial and temporal relationships
in biological systems, including intercellular signaling as well as environmentally-cued …

RNF43/ZNRF3 loss predisposes to hepatocellular-carcinoma by impairing liver regeneration and altering the liver lipid metabolic ground-state

G Belenguer, G Mastrogiovanni, C Pacini, Z Hall… - Nature …, 2022 - nature.com
Abstract RNF43/ZNRF3 negatively regulate WNT signalling. Both genes are mutated in
several types of cancers, however, their contribution to liver disease is unknown. Here we …

msIQuant–quantitation software for mass spectrometry imaging enabling fast access, visualization, and analysis of large data sets

P Kallback, A Nilsson, M Shariatgorji… - Analytical …, 2016 - ACS Publications
This paper presents msIQuant, a novel instrument-and manufacturer-independent
quantitative mass spectrometry imaging software suite that uses the standardized open …