[HTML][HTML] Antibacterial gas therapy: strategies, advances, and prospects

TY Wang, XY Zhu, FG Wu - Bioactive Materials, 2023 - Elsevier
One of the challenges posed by current antibacterial therapy is that the expanded and
massive use of antibiotics endows bacteria with the ability to resist almost all kinds of …

Role of reactive oxygen species (ROS) in therapeutics and drug resistance in cancer and bacteria

AT Dharmaraja - Journal of Medicinal Chemistry, 2017 - ACS Publications
Evading persistent drug resistance in cancer and bacteria is quintessential to restore health
in humans, and impels intervention strategies. A distinct property of the cancer phenotype is …

Gas-mediated cancer bioimaging and therapy

L Chen, SF Zhou, L Su, J Song - ACS nano, 2019 - ACS Publications
Gas-involving cancer theranostics have attracted considerable attention in recent years due
to their high therapeutic efficacy and biosafety. We have reviewed the recent significant …

External stimuli-responsive gasotransmitter prodrugs: Chemistry and spatiotemporal release

X Ji, Z Zhong - Journal of Controlled Release, 2022 - Elsevier
Gasotransmitters like nitric oxide, carbon monoxide, and hydrogen sulfide with unique
pleiotropic pharmacological effects in mammals are an emerging therapeutic modality for …

A glutathione activatable ion channel induces apoptosis in cancer cells by depleting intracellular glutathione levels

JA Malla, RM Umesh, S Yousf, S Mane… - Angewandte Chemie …, 2020 - Wiley Online Library
Cancer cells use elevated glutathione (GSH) levels as an inner line of defense to evade
apoptosis and develop drug resistance. In this study, we describe a novel 2, 4 …

Advances in BODIPY photocleavable protecting groups

PK Singh, P Majumdar, SP Singh - Coordination Chemistry Reviews, 2021 - Elsevier
Photoactivatable protecting groups (PPGs) or caged compounds are beneficial tools for
spatiotemporal controlled release of bioagents, fluorescent probes, polymerization initiators …

[HTML][HTML] Click chemistry and drug delivery: A bird's-eye view

SM Kondengadan, S Bansal, C Yang, D Liu… - … Pharmaceutica Sinica B, 2023 - Elsevier
Click chemistry has been proven to be very useful in drug delivery. Due to the availability of
a large number of click reactions with a various characteristics, selection of appropriate …

Advances in Gas Therapeutics for Wound Healing: Mechanisms, Delivery Materials, and Prospects

J Ding, K Xu, H Xu, J Ji, Y Qian, J Shen - Small Structures, 2024 - Wiley Online Library
Wound repair, particularly chronic nonhealing wound repair, is a global health issue that
affects millions of people worldwide. As an effective and safe therapeutic reagent, gas …

Cysteine-activated hydrogen sulfide (H 2 S) delivery through caged carbonyl sulfide (COS) donor motifs

Y Zhao, AK Steiger, MD Pluth - Chemical communications, 2018 - pubs.rsc.org
Hydrogen sulfide (H2S) is an important biomolecule, and controllable H2S donors are
needed to investigate H2S biological functions. Here we utilize cysteine-mediated …

Glutathione-Responsive Sulfur Dioxide-Releasing Dendronized Chitooligosaccharide Polymer for Effective Treatment of Multidrug-Resistant Bacterial Infection

H Yu, J Liu, Q Lin, J Liu, S Yu, P Sun, J Lin - Chemical Engineering Journal, 2023 - Elsevier
Treating bacterial infection is emerging as a major obstacle to human public health today. As
a kind of long-established and widely used food preservative, the lipophilic gas sulfur …