Connective tissue growth factor (CTGF) is a key signaling and regulatory molecule involved
in different biological processes, such as cell proliferation, angiogenesis, and wound …

Thrombospondins TSP-1 and TSP-2 are potent endogenous inhibitors of angiogenesis.
They inhibit angiogenesis through direct effects on endothelial cell migration, proliferation …

A central goal of HIV-1 vaccine research is the elicitation of antibodies capable of
neutralizing diverse primary isolates of HIV-1. Here we show that focusing the immune …

Thrombospondins are evolutionarily conserved, calcium-binding glycoproteins that undergo
transient or longer-term interactions with other extracellular matrix components. They share …

RTN4-binding proteins were widely studied as" NoGo" receptors, but their physiological
interactors and roles remain elusive. Similarly, BAI adhesion-GPCRs were associated with …

The CCN proteins are key signalling and regulatory molecules involved in many vital
biological functions, including cell proliferation, angiogenesis, tumourigenesis and wound …

The four vertebrate R-spondin proteins are secreted agonists of the canonical Wnt/β-catenin
signaling pathway. These proteins are approximately 35 kDa, and are characterized by two …

Thrombospondin-1 (TSP-1) was studied in the 1980s as a major component of platelet α-
granules released upon platelet activation and also as a cell adhesion molecule. In 1993 …

Apicomplexan parasites constitute one of the most significant groups of pathogens infecting
humans and animals. The liver stage sporozoites of Plasmodium spp. and tachyzoites of …

Thrombospondin-1 (TSP1) can inhibit angiogenic responses directly by interacting with
VEGF and indirectly by engaging several endothelial cell TSP1 receptors. We now describe …