Overview of hepatitis B viral replication and genetic variability

S Tong, P Revill - Journal of hepatology, 2016 - Elsevier
Chronic infection with hepatitis B virus (HBV) greatly increases the risk for liver cirrhosis and
hepatocellular carcinoma (HCC). HBV isolates worldwide can be divided into ten genotypes …

Distribution of HBV genotypes in Latin America

MV Alvarado-Mora, JRR Pinho - Antiviral therapy, 2013 - journals.sagepub.com
Approximately 2 billion people worldwide are infected with HBV, and 350 million people are
chronic carriers. HBV is classified into nine genotypes (A to I). Genotype F is the most …

Quantitative longitudinal evaluations of hepatitis delta virus RNA and hepatitis B virus DNA shows a dynamic, complex replicative profile in chronic hepatitis B and D

M Schaper, F Rodriguez-Frias, R Jardi, D Tabernero… - Journal of …, 2010 - Elsevier
BACKGROUND & AIMS: This study presents a real-time reverse-transcription PCR (rt-RT-
PCR) assay for hepatitis delta virus (HDV) RNA quantification, designed to clarify the …

Direct effects of hepatitis B virus-encoded proteins and chronic infection in liver cancer development

M Ringelhan, M Heikenwalder, U Protzer - Digestive diseases, 2013 - karger.com
Hepatocellular carcinoma (HCC) ranks as the third leading cause of cancer-related death
worldwide with currently limited treatment options. Chronic hepatitis B virus (HBV) infection …

[HTML][HTML] HBV endemicity in Mexico is associated with HBV genotypes H and G

S Roman, A Panduro - World journal of gastroenterology: WJG, 2013 - ncbi.nlm.nih.gov
Hepatitis B virus (HBV) genotypes have distinct genetic and geographic diversity and may
be associated with specific clinical characteristics, progression, severity of disease and …

Long‐term benefits of interferon‐α therapy in children with HBeAg‐positive immune‐active chronic hepatitis B

L Wang, J Zhao, J Liu, C Zhen, M Zhang… - Journal of Viral …, 2021 - Wiley Online Library
The long‐term benefits of interferon‐α (IFN‐α) treatment in children with chronic hepatitis B
(CHB) remain unclear. We conducted a retrospective and real‐world study to evaluate the …

[HTML][HTML] Molecular characterization of the Hepatitis B virus genotypes in Colombia: a Bayesian inference on the genotype F

MVA Mora, CM Romano, MS Gomes-Gouvêa… - Infection, genetics and …, 2011 - Elsevier
Hepatitis B is a worldwide health problem affecting about 2 billion people and more than
350 million are chronic carriers of the virus. Nine HBV genotypes (A to I) have been …

HIV/hepatitis B virus co-infection: current challenges and new strategies

K Lacombe, J Bottero, M Lemoine… - Journal of …, 2010 - academic.oup.com
Chronic hepatitis B virus (HBV) infection, which affects 7%–10% of HIV-infected patients, is
associated with an increased frequency of AIDS-related and non-AIDS-related clinical …

Hepatitis B virus genotype G epidemiology and co-infection with genotype A in Canada

C Osiowy, D Gordon, J Borlang… - Journal of General …, 2008 - microbiologyresearch.org
Hepatitis B virus (HBV) genotype G (HBV/G) is an unusual variant, and little is known about
its epidemiology and natural history, particularly the requirement for a co-infecting HBV …

A literature review of mathematical models of hepatitis B virus transmission applied to immunization strategies from 1994 to 2015

P Liang, J Zu, G Zhuang - Journal of epidemiology, 2018 - jstage.jst.go.jp
ABSTRACT A mathematical model of the transmission dynamics of infectious disease is an
important theoretical epidemiology method, which has been used to simulate the prevalence …