Salivary biomarkers and their application in the diagnosis and monitoring of the most common oral pathologies

L Melguizo-Rodríguez, VJ Costela-Ruiz… - International journal of …, 2020 - mdpi.com
Saliva is a highly versatile biological fluid that is easy to gather in a non-invasive manner—
and the results of its analysis complement clinical and histopathological findings in the …

Inflammatory mediators in oral cancer: pathogenic mechanisms and diagnostic potential

SE Niklander - Frontiers in Oral Health, 2021 - frontiersin.org
Approximately 15% of cancers are attributable to the inflammatory process, and growing
evidence supports an association between oral squamous cell carcinoma (OSCC) and …

Diagnostic value of salivary miRNA in head and neck squamous cell cancer: systematic review and meta-analysis

JW Kang, YG Eun, YC Lee - International Journal of Molecular Sciences, 2021 - mdpi.com
Several studies have highlighted the diagnostic potential of salivary microRNA (miRNA) in
head and neck squamous cell cancer (HNSCC). The purpose of this meta-analysis was to …

Salivary micro-RNA and oral squamous cell carcinoma: A systematic review

M Menini, E De Giovanni, F Bagnasco… - Journal of personalized …, 2021 - mdpi.com
Oral squamous cell carcinoma (OSCC) is a widespread malignancy with high mortality. In
particular, a delay in its diagnosis dramatically decreases the survival rate. The aim of this …

Plasmon resonance biosensor for interleukin-1β point-of-care determination: A tool for early periodontitis diagnosis

N Cennamo, D Bencivenga, M Annunziata, F Arcadio… - Iscience, 2024 - cell.com
Among pro-inflammatory cytokines, Interleukin-1β is crucially involved in several
inflammatory-based diseases and even cancer. Increased Interleukin-1β levels in oral fluids …

IL-1/IL-1R signaling in head and neck cancer

SE Niklander, C Murdoch, KD Hunter - Frontiers in Oral Health, 2021 - frontiersin.org
Decades ago, the study of cancer biology was mainly focused on the tumor itself, paying
little attention to the tumor microenvironment (TME). Currently, it is well recognized that the …

Salivary biomarkers in breast cancer diagnosis: a systematic review and diagnostic meta‐analysis

M Koopaie, S Kolahdooz, M Fatahzadeh… - Cancer …, 2022 - Wiley Online Library
Background Salivary diagnostics and their utility as a nonaggressive approach for breast
cancer diagnosis have been extensively studied in recent years. This meta‐analysis …

Salivary noncoding RNA in the diagnosis of pancreatic cancer: Systematic review and meta‐analysis

M Koopaie, S Kolahdooz, M Fatahzadeh… - European journal of …, 2022 - Wiley Online Library
Background Pancreatic cancer is considered one of the most deadly malignancies, primarily
because of its diagnostic challenges. We performed a systematic review and diagnostic …

Association of salivary Cathepsin B in different histological grades among patients presenting with oral squamous cell carcinoma

A Shabbir, H Waheed, S Ahmed, SS Shaikh… - BMC Oral Health, 2022 - Springer
Background Oral cancer is considered a major public health problem due to its high
mortality and morbidity rates. Survival rate of OSCC can be significantly improved by using …

Diagnostic value of circRNAs as potential biomarkers in oral squamous cell carcinoma: a meta-analysis

M Wang, L Zhang, W Ren, S Li, K Zhi, J Zheng… - Frontiers in …, 2021 - frontiersin.org
Introduction Circular RNAs (CircRNAs), an emerging non-coding RNA, have been
demonstrated to be involved in tumorigenesis, metastasis, and cancer progression, and …