Objective To establish the evidence of therapeutic hypothermia for newborns with hypoxic
ischemic encephalopathy (HIE). Data Sources Cochrane Central Register of Controlled …

Background Therapeutic hypothermia (TH) is regarded as the most efficacious therapy for
neonatal hypoxic encephalopathy. However, limitations in previous systematic reviews and …

Background Whether hypothermic therapy improves neurodevelopmental outcomes in
newborn infants with asphyxial encephalopathy is uncertain. Methods We performed a …

Objective To determine whether moderate hypothermia after hypoxic-ischaemic
encephalopathy in neonates improves survival and neurological outcome at 18 months of …

Background Newborn animal studies and pilot studies in humans suggest that mild
hypothermia following peripartum hypoxia‐ischaemia in newborn infants may reduce …

The contributors to this statement were selected to ensure expertise in all the disciplines
relevant to post–cardiac arrest care. In an attempt to make this document universally …

Background Cerebral hypothermia can improve outcome of experimental perinatal hypoxia-
ischaemia. We did a multicentre randomised controlled trial to find out if delayed head …

AIM OF THE REVIEW: To review the epidemiology, pathophysiology, treatment and
prognostication in relation to the post-cardiac arrest syndrome. METHODS: Relevant articles …

● Unconscious adult patients with spontaneous circulation after out-of-hospital cardiac
arrest should be cooled to 32 C to 34 C for 12 to 24 hours when the initial rhythm was …

Background. Infant and under-5 childhood mortality rates in developing countries have
declined significantly in the past 2 to 3 decades. However, 2 critical indicators, maternal and …