[HTML][HTML] Haemonchosis in Sheep and Goats, Control Strategies and Development of Vaccines against Haemonchus contortus

I Adduci, F Sajovitz, B Hinney, K Lichtmannsperger… - Animals, 2022 - mdpi.com
Simple Summary Haemonchus contortus is the most pathogenic blood-feeding parasitic
nematode in sheep and goats, threatening animal welfare and causing tremendous …

[HTML][HTML] Improving helminth genome resources in the post-genomic era

SR Doyle - Trends in parasitology, 2022 - cell.com
Rapid advancement in high-throughput sequencing and analytical approaches has seen a
steady increase in the generation of genomic resources for helminth parasites. Now …

[HTML][HTML] Advances in the Development of Anti-Haemonchus contortus Vaccines: Challenges, Opportunities, and Perspectives

M Ehsan, RS Hu, QL Liang, JL Hou, X Song, R Yan… - Vaccines, 2020 - mdpi.com
The gastrointestinal nematode parasite Haemonchus contortus (H. contortus) is a resident of
tropical and subtropical regions worldwide that imposes significant production losses …

High throughput LC-MS/MS-based proteomic analysis of excretory-secretory products from short-term in vitro culture of Haemonchus contortus

T Wang, G Ma, CS Ang, PK Korhonen, AV Koehler… - Journal of …, 2019 - Elsevier
Parasitic nematodes of humans, animals and plants have a major, adverse impact on global
health and agricultural production worldwide. To cope with their surrounding environment in …

[HTML][HTML] Dafachronic acid promotes larval development in Haemonchus contortus by modulating dauer signalling and lipid metabolism

G Ma, T Wang, PK Korhonen, ND Young, S Nie… - PLoS …, 2019 - journals.plos.org
Here, we discovered an endogenous dafachronic acid (DA) in the socioeconomically
important parasitic nematode Haemonchus contortus. We demonstrate that DA promotes …

[HTML][HTML] The Proteome and Lipidome of Extracellular Vesicles from Haemonchus contortus to Underpin Explorations of Host–Parasite Cross–Talk

T Wang, TF Koukoulis, LJ Vella, H Su… - International Journal of …, 2023 - mdpi.com
Many parasitic worms have a major adverse impact on human and animal populations
worldwide due to the chronicity of their infections. There is a growing body of evidence …

[HTML][HTML] Thermal proteome profiling reveals Haemonchus orphan protein HCO_011565 as a target of the nematocidal small molecule UMW-868

AC Taki, T Wang, NN Nguyen, CS Ang… - Frontiers in …, 2022 - frontiersin.org
Parasitic roundworms (nematodes) cause destructive diseases, and immense suffering in
humans and other animals around the world. The control of these parasites relies heavily on …

[HTML][HTML] High-quality nuclear genome for Sarcoptes scabiei—A critical resource for a neglected parasite

PK Korhonen, RB Gasser, G Ma, T Wang… - PLoS Neglected …, 2020 - journals.plos.org
The parasitic mite Sarcoptes scabiei is an economically highly significant parasite of the skin
of humans and animals worldwide. In humans, this mite causes a neglected tropical disease …

[HTML][HTML] A high-throughput phenotypic screen of the 'Pandemic Response Box'identifies a quinoline derivative with significant anthelmintic activity

HT Shanley, AC Taki, JJ Byrne, A Jabbar, TNC Wells… - Pharmaceuticals, 2022 - mdpi.com
Parasitic nematodes cause diseases in livestock animals and major economic losses to the
agricultural industry worldwide. Nematodes of the order Strongylida, including Haemonchus …

Advancing Strongyloides omics data: bridging the gap with Caenorhabditis elegans

R Al-Jawabreh, D Lastik… - … of the Royal …, 2024 - royalsocietypublishing.org
Among nematodes, the free-living model organism Caenorhabditis elegans boasts the most
advanced portfolio of high-quality omics data. The resources available for parasitic …