Altered cell adhesion and glycosylation promote cancer immune suppression and metastasis
Cell-cell interactions and cell adhesion are key mediators of cancer progression and
facilitate hallmarks of cancer including immune evasion and metastatic dissemination. Many …
facilitate hallmarks of cancer including immune evasion and metastatic dissemination. Many …
Cancer cell adhesion and metastasis: selectins, integrins, and the inhibitory potential of heparins
G Bendas, L Borsig - International journal of cell biology, 2012 - Wiley Online Library
Cell adhesion molecules play a significant role in cancer progression and metastasis. Cell‐
cell interactions of cancer cells with endothelium determine the metastatic spread. In …
cell interactions of cancer cells with endothelium determine the metastatic spread. In …
Transmembrane mucins: signaling receptors at the intersection of inflammation and cancer
JPM van Putten, K Strijbis - Journal of innate immunity, 2017 - karger.com
Mucosal surfaces line our body cavities and provide the interaction surface between
commensal and pathogenic microbiota and the host. The barrier function of the mucosal …
commensal and pathogenic microbiota and the host. The barrier function of the mucosal …
Vascular niche E-selectin regulates hematopoietic stem cell dormancy, self renewal and chemoresistance
IG Winkler, V Barbier, B Nowlan, RN Jacobsen… - Nature medicine, 2012 - nature.com
The microenvironment, or niche, surrounding a stem cell largely governs its cellular fate.
Two anatomical niches for hematopoietic stem cells (HSCs) have been reported in the bone …
Two anatomical niches for hematopoietic stem cells (HSCs) have been reported in the bone …
Endothelial microRNAs regulating the NF‐κB pathway and cell adhesion molecules during inflammation
The surface of endothelial cells is covered with cell adhesion molecules, including E‐
selectin, intercellula adhesion molecule 1 (ICAM‐1), and vascular cell adhesion molecule 1 …
selectin, intercellula adhesion molecule 1 (ICAM‐1), and vascular cell adhesion molecule 1 …
Unmasking fucosylation: from cell adhesion to immune system regulation and diseases
J Li, HC Hsu, JD Mountz, JG Allen - Cell chemical biology, 2018 - cell.com
Fucosylation is a biological process broadly observed in vertebrates, invertebrates, plants,
bacteria, and fungi. Fucose moieties on cell-surface glycans are increasingly recognized as …
bacteria, and fungi. Fucose moieties on cell-surface glycans are increasingly recognized as …
Selectins promote tumor metastasis
Cancer metastasis is facilitated by cell–cell interactions between cancer cells and
endothelial cells in distant tissues. In addition, cancer cell interactions with platelets and …
endothelial cells in distant tissues. In addition, cancer cell interactions with platelets and …
[HTML][HTML] The p38 pathway, a major pleiotropic cascade that transduces stress and metastatic signals in endothelial cells
By gating the traffic of molecules and cells across the vessel wall, endothelial cells play a
central role in regulating cardiovascular functions and systemic homeostasis and in …
central role in regulating cardiovascular functions and systemic homeostasis and in …
Generation of 3D functional microvascular networks with human mesenchymal stem cells in microfluidic systems
The generation of functional microvascular networks is critical for the development of
advanced in vitro models to replicate pathophysiological conditions. Mural cells provide …
advanced in vitro models to replicate pathophysiological conditions. Mural cells provide …
Molecular interactions in cancer cell metastasis
SA Brooks, HJ Lomax-Browne, TM Carter, CE Kinch… - Acta histochemica, 2010 - Elsevier
Metastasis, the process by which cancer cells leave the primary tumour, disseminate and
form secondary tumours at anatomically distant sites, is a serious clinical problem as it is …
form secondary tumours at anatomically distant sites, is a serious clinical problem as it is …