Breathing matters
Breathing is a well-described, vital and surprisingly complex behaviour, with behavioural
and physiological outputs that are easy to directly measure. Key neural elements for …
and physiological outputs that are easy to directly measure. Key neural elements for …
Patient-specific cardiovascular computational modeling: diversity of personalization and challenges
RA Gray, P Pathmanathan - Journal of cardiovascular translational …, 2018 - Springer
Patient-specific computer models have been developed representing a variety of aspects of
the cardiovascular system spanning the disciplines of electrophysiology, electromechanics …
the cardiovascular system spanning the disciplines of electrophysiology, electromechanics …
Simulation and synthesis in medical imaging
This editorial introduces the Special Issue on Simulation and Synthesis in Medical Imaging.
In this editorial, we define so-far ambiguous terms of simulation and synthesis in medical …
In this editorial, we define so-far ambiguous terms of simulation and synthesis in medical …
[HTML][HTML] Uncertainty and variability in models of the cardiac action potential: Can we build trustworthy models?
RH Johnstone, ETY Chang, R Bardenet… - Journal of molecular and …, 2016 - Elsevier
Cardiac electrophysiology models have been developed for over 50 years, and now include
detailed descriptions of individual ion currents and sub-cellular calcium handling. It is …
detailed descriptions of individual ion currents and sub-cellular calcium handling. It is …
Uncertainty and variability in computational and mathematical models of cardiac physiology
Key points Mathematical and computational models of cardiac physiology have been an
integral component of cardiac electrophysiology since its inception, and are collectively …
integral component of cardiac electrophysiology since its inception, and are collectively …
Verification of cardiac mechanics software: benchmark problems and solutions for testing active and passive material behaviour
Models of cardiac mechanics are increasingly used to investigate cardiac physiology. These
models are characterized by a high level of complexity, including the particular anisotropic …
models are characterized by a high level of complexity, including the particular anisotropic …
Comprehensive uncertainty quantification and sensitivity analysis for cardiac action potential models
Recent efforts to ensure the reliability of computational model-based predictions in
healthcare, such as the ASME V&V40 Standard, emphasize the importance of uncertainty …
healthcare, such as the ASME V&V40 Standard, emphasize the importance of uncertainty …
Facing the challenge of mammalian neural microcircuits: taking a few breaths may help
JL Feldman, K Kam - The Journal of physiology, 2015 - Wiley Online Library
Breathing in mammals is a seemingly straightforward behaviour controlled by the brain. A
brainstem nucleus called the preBötzinger Complex sits at the core of the neural circuit …
brainstem nucleus called the preBötzinger Complex sits at the core of the neural circuit …
Considering discrepancy when calibrating a mechanistic electrophysiology model
Uncertainty quantification (UQ) is a vital step in using mathematical models and simulations
to take decisions. The field of cardiac simulation has begun to explore and adopt UQ …
to take decisions. The field of cardiac simulation has begun to explore and adopt UQ …
Evaluation of an open-source pipeline to create patient-specific left atrial models: a reproducibility study
This work presents an open-source software pipeline to create patient-specific left atrial
models with fibre orientations and a fibrDEFAULTosis map, suitable for electrophysiology …
models with fibre orientations and a fibrDEFAULTosis map, suitable for electrophysiology …