The ABO blood group system, discovered by Karl Landsteiner in 1900, 1 is fundamental to
the safety of blood transfusion, which requires identification of weak phenotypes or …

Abstract Background and Summary: We review the transcriptional regulation of ABO
expression and discuss variants in the promoter and erythroid cell-specific regulatory region …

In the era of blood group genomics, reference collections of complete and fully resolved
blood group gene alleles have gained high importance. For most blood groups, however …

BACKGROUND Genotyping has expanded the number red blood cell (RBC) and platelet
(PLT) antigens that can readily be typed, but often represents an additional testing cost. The …

Background Immunohematology reference laboratories provide red blood cell (RBC),
platelet (PLT), and neutrophil typing to resolve complex cases, using serology and …

Background: Next-generation sequencing (NGS) technology has been recently introduced
into blood group genotyping; however, there are few studies using NGS-based blood group …

Abstract Background and Objectives Mixed‐field agglutination in ABO phenotyping (A3, B3)
has been linked to genetically different blood cell populations such as in chimerism, or to …

Background Accurate ABO typing is essential for preventing ABO incompatibility reactions.
However, the causes of ABO grouping discrepancy has not been sufficiently studied, and it …

ABO blood group antigens are critical determinants of immunologic self and non-self and
are ubiquitously expressed on all cellular tissues. Antibodies against non-self ABO antigens …

Background Nucleotide mutations in the ABO gene may reduce the activity of
glycosyltransferase, resulting in lower levels of A or B antigen expression in red blood cells …