Epstein–Barr virus oncoprotein–driven B cell metabolism remodeling
EM Burton, BE Gewurz - PLoS Pathogens, 2022 - journals.plos.org
The γ-herpesvirus Epstein–Barr virus (EBV) persistently infects> 95% of adults worldwide
and contributes to 200,000 cancers annually [1]. EBV uses latency programs to convert …
and contributes to 200,000 cancers annually [1]. EBV uses latency programs to convert …
[HTML][HTML] Interplay between the DNA damage response and the life cycle of DNA tumor viruses
CJ Studstill, M Mac, CA Moody - Tumour Virus Research, 2023 - Elsevier
Approximately 20% of human cancers are associated with virus infection. DNA tumor viruses
can induce tumor formation in host cells by disrupting the cell's DNA replication and repair …
can induce tumor formation in host cells by disrupting the cell's DNA replication and repair …
A multi-omics approach to Epstein-Barr virus immortalization of B-cells reveals EBNA1 chromatin pioneering activities targeting nucleotide metabolism
RJ Lamontagne, SS Soldan, C Su, A Wiedmer… - PLoS …, 2021 - journals.plos.org
Epstein-Barr virus (EBV) immortalizes resting B-lymphocytes through a highly orchestrated
reprogramming of host chromatin structure, transcription and metabolism. Here, we use a …
reprogramming of host chromatin structure, transcription and metabolism. Here, we use a …
Epstein-Barr virus nuclear antigen 3C (EBNA3C) interacts with the metabolism sensing C-terminal binding protein (CtBP) repressor to upregulate host genes
M Ohashi, M Hayes, K McChesney… - PLoS …, 2021 - journals.plos.org
Epstein-Barr virus (EBV) infection is associated with the development of specific types of
lymphoma and some epithelial cancers. EBV infection of resting B-lymphocytes in vitro …
lymphoma and some epithelial cancers. EBV infection of resting B-lymphocytes in vitro …
Novel replisome-associated proteins at cellular replication forks in EBV-transformed B lymphocytes
Epstein-Barr virus (EBV) is an oncogenic herpesvirus and WHO class 1 carcinogen that
resides in B lymphocytes of nearly all humans. While silent in most, EBV can cause endemic …
resides in B lymphocytes of nearly all humans. While silent in most, EBV can cause endemic …