Effects of safinamide on non-motor, cognitive, and behavioral symptoms in fluctuating Parkinson's disease patients: a prospective longitudinal study
R De Micco, S Satolli, M Siciliano, A De Mase… - Neurological …, 2022 - Springer
Introduction Parkinson's disease (PD) patients in chronic levodopa treatment may
experience motor and non-motor fluctuations, which may affect their quality of life …
experience motor and non-motor fluctuations, which may affect their quality of life …
Integrative Pharmacology in the Treatment of Substance Use Disorders
J Donlon, P Kumari, SP Varghese, M Bai… - Journal of Dual …, 2024 - Taylor & Francis
The detrimental physical, mental, and socioeconomic effects of substance use disorders
(SUDs) have been apparent to the medical community for decades. However, it has become …
(SUDs) have been apparent to the medical community for decades. However, it has become …
Neuronal activity of the medial prefrontal cortex, nucleus accumbens, and basolateral amygdala in conditioned taste aversion and conditioned place preference …
CY Ou, YH Yu, CW Wu, A Kozłowska… - Frontiers in …, 2023 - frontiersin.org
To re-examine the paradoxical effect hypothesis of abused drugs, the present study
concerned whether different doses of morphine disparately affect neuronal activity and …
concerned whether different doses of morphine disparately affect neuronal activity and …
The Role of Dopamine D1 and D3 Receptors in N-Methyl-D-Aspartate (NMDA)/GlycineB Site-Regulated Complex Cognitive Behaviors following Repeated Morphine …
Y Wang, F Yin, H Guo, J Zhang, P Yan… - International Journal of …, 2017 - academic.oup.com
Background: Opiate addiction is associated with complex cognitive impairment, which
contributes to the development of compulsive drug use and relapses. Dopamine and N …
contributes to the development of compulsive drug use and relapses. Dopamine and N …
A conantokin peptide con-T [M8Q] inhibits morphine dependence with high potency and low side effects
Z Liu, Z Yu, S Yu, C Zhu, M Dong, W Mao, J Hu… - Marine drugs, 2021 - mdpi.com
N-methyl-D-aspartate receptor (NMDAR) antagonists have been found to be effective to
inhibit morphine dependence. However, the discovery of the selective antagonist for …
inhibit morphine dependence. However, the discovery of the selective antagonist for …
Ketamine and hydroxynorketamine as novel pharmacotherapies for the treatment of Opioid-Use Disorders
O Anna, A Michael, M Apostolakis… - Biological … - biologicalpsychiatryjournal.com
Opioid use disorder (OUD) has reached epidemic proportions, with many countries facing
high opioid use and related fatalities. Although currently-prescribed medications for OUD …
high opioid use and related fatalities. Although currently-prescribed medications for OUD …