Precision medicine in complex diseases—Molecular subgrouping for improved prediction and treatment stratification
Complex diseases are caused by a combination of genetic, lifestyle, and environmental
factors and comprise common noncommunicable diseases, including allergies …
factors and comprise common noncommunicable diseases, including allergies …
Stimuli‐responsive organic near‐infrared photoacoustic probes
Q Shen, L Wang, X Ruan, N Li, W Wang… - Advanced Functional …, 2023 - Wiley Online Library
Photoacoustic (PA) imaging is an emerging biomedical imaging technique with the features
of non‐invasiveness and non‐ionization. It takes advantage of the photothermal effect of PA …
of non‐invasiveness and non‐ionization. It takes advantage of the photothermal effect of PA …
Combination of exercise and GLP-1 receptor agonist treatment reduces severity of metabolic syndrome, abdominal obesity, and inflammation: a randomized …
Background Identifying and reducing cardiometabolic risks driven by obesity remains a
healthcare challenge. The metabolic syndrome is associated with abdominal obesity and …
healthcare challenge. The metabolic syndrome is associated with abdominal obesity and …
Contribution of specific ceramides to obesity-associated metabolic diseases
P Hammerschmidt, JC Brüning - Cellular and Molecular Life Sciences, 2022 - Springer
Ceramides are a heterogeneous group of bioactive membrane sphingolipids that play
specialized regulatory roles in cellular metabolism depending on their characteristic fatty …
specialized regulatory roles in cellular metabolism depending on their characteristic fatty …
Obesity and cardiovascular disease: an ESC clinical consensus statement
KC Koskinas, EM Van Craenenbroeck… - European Heart …, 2024 - academic.oup.com
The global prevalence of obesity has more than doubled over the past four decades,
currently affecting more than a billion individuals. Beyond its recognition as a high-risk …
currently affecting more than a billion individuals. Beyond its recognition as a high-risk …
Methods for the identification and characterization of extracellular vesicles in cardiovascular studies: from exosomes to microvesicles
Extracellular vesicles (EVs) are nanosized vesicles with a lipid bilayer that are released from
cells of the cardiovascular system, and are considered important mediators of intercellular …
cells of the cardiovascular system, and are considered important mediators of intercellular …
Perivascular adipose tissue as a source of therapeutic targets and clinical biomarkers: A clinical consensus statement from the European Society of Cardiology …
Obesity is a modifiable cardiovascular risk factor, but adipose tissue (AT) depots in humans
are anatomically, histologically, and functionally heterogeneous. For example, visceral AT is …
are anatomically, histologically, and functionally heterogeneous. For example, visceral AT is …
Extracellular vesicles in atherothrombosis: From biomarkers and precision medicine to therapeutic targets
L Badimon, T Padro, G Arderiu, G Vilahur… - Immunological …, 2022 - Wiley Online Library
Atherosclerotic cardiovascular disease (ASCVD) remains the leading cause of global
mortality. Extracellular vesicles (EVs) are small phospholipid vesicles that convey molecular …
mortality. Extracellular vesicles (EVs) are small phospholipid vesicles that convey molecular …
Insulin: The master regulator of glucose metabolism
Insulin is the master regulator of glucose, lipid, and protein metabolism. Following ingestion
of an oral glucose load or mixed meal, the plasma glucose concentration rises, insulin …
of an oral glucose load or mixed meal, the plasma glucose concentration rises, insulin …
[HTML][HTML] Metabolomics of extracellular vesicles: a future promise of multiple clinical applications
YL Wu, WJ Chen, M Guo, Q Tan, E Zhou… - International Journal …, 2022 - ncbi.nlm.nih.gov
Extracellular vesicles (EVs) can contain DNA, RNA, proteins and metabolic molecules from
primary origins; they are coated with a phospholipid bilayer membrane and released by …
primary origins; they are coated with a phospholipid bilayer membrane and released by …