Toxoplasma gondii is an obligate intracellular parasite that chronically infects a third of
humans. It can cause life-threatening encephalitis in immune-compromised individuals …

Macrophages are the major host cells for Leishmania parasites, and determine the fate of
infection by either limiting or allowing growth of the parasites, resulting in development or …

Dendritic cells and macrophages are integral parts of the innate immune system and
gatekeepers against infection. The protozoan pathogen, Toxoplasma gondii, is known to …

Monocytes are critical cells of the immune system but their role as effectors is relatively
poorly understood, as they have long been considered only as precursors of tissue …

Microorganisms have been identified in tumor specimens for over a century. It is only in
recent years that tumor-associated microbiota has become a rapidly expanding field …

Infections are highly orchestrated and dynamic processes, which involve both pathogen and
host. Transcriptional profiling at the single-cell level enables the analysis of cell diversity …

Monocytes play a crucial role in immunity and tissue homeostasis. They constitute the first
line of defense during the inflammatory process, playing a role in the pathogenesis and …

Host-parasite interactions include complex interplays between an invading and a defending
organism, each continuously adapting to gain the upper hand. The protozoan parasite …

Over the past decade, single-cell RNA sequencing (scRNA-seq) has revolutionized the field
of transcriptomics, enabling the acquisition of unprecedented insights and fostering research …

Dual RNA-seq captures both host and pathogen transcriptomes at the site of infection,
facilitating an exploration of processes that play an essential role in pathogenesis and the …