Targeting multiple signaling pathways in cancer: The rutin therapeutic approach

Z Nouri, S Fakhri, K Nouri, CE Wallace, MH Farzaei… - Cancers, 2020 - mdpi.com
Multiple dysregulated signaling pathways are implicated in the pathogenesis of cancer. The
conventional therapies used in cancer prevention/treatment suffer from low efficacy …

From ancient to emerging infections: the odyssey of viruses in the male genital tract

A Le Tortorec, G Matusali, D Mahé… - Physiological …, 2020 - journals.physiology.org
The male genital tract (MGT) is the target of a number of viral infections that can have
deleterious consequences at the individual, offspring, and population levels. These …

Knowledge, attitudes, and practices among Indonesian urban communities regarding HPV infection, cervical cancer, and HPV vaccination

H Winarto, M Habiburrahman, M Dorothea, A Wijaya… - PloS one, 2022 - journals.plos.org
Background Few studies explored Indonesian understanding of cervical cancer (CC) and
the human papillomavirus (HPV) vaccination. We aimed to investigate the association …

A biochemistry‐oriented drug design: synthesis, anticancer activity, enzymes inhibition, molecular docking studies of novel 1, 2, 4-triazole derivatives

K Yuriy, G Kusdemir, P Volodymyr… - Journal of …, 2024 - Taylor & Francis
In this study, we researched the reactions of 5-(5-bromofuran-2-yl)-4-methyl-1, 2, 4-triazole-3-
thiol and 5-thiophene-(3-ylmethyl)-4R-1, 2, 4-triazole-3-thiols with some halogen-containing …

Health inequity drives disease biology to create disparities in prostate cancer outcomes

WG Nelson, OW Brawley, WB Isaacs… - The Journal of …, 2022 - Am Soc Clin Investig
Prostate cancer exerts a greater toll on African American men than on White men of
European descent (hereafter referred to as European American men): the disparity in …

Polyploid giant cancer cells generated from human cytomegalovirus-infected prostate epithelial cells

F Bouezzedine, R El Baba, S Haidar Ahmad… - Cancers, 2023 - mdpi.com
Simple Summary Prostate cancer remains a leading cause of death in men worldwide.
Polyploid giant cancer cells (PGCCs) and chromosomal instability have been proposed to …

Possible role of HPV/EBV coinfection in anoikis resistance and development in prostate cancer

JS Nahand, K Khanaliha, H Mirzaei, M Moghoofei… - BMC cancer, 2021 - Springer
Background This study aimed to evaluate the possible role of human papillomavirus (HPV)
and Epstein–Barr virus (EBV) coinfection as an etiological factor for prostate cancer (PCa) …

Detection and characterization of latency stage of EBV and histopathological analysis of prostatic adenocarcinoma tissues

K Ahmed, A Sheikh, S Fatima, G Haider, K Ghias… - Scientific Reports, 2022 - nature.com
The pathophysiology of prostate cancer involves both genetic and acquired factors,
including pathogens, such as viruses. A limited number of studies have shown the presence …

Combined analysis and validation for DNA methylation and gene expression profiles associated with prostate cancer

Y Tong, Y Song, S Deng - Cancer Cell International, 2019 - Springer
Abstract Background Prostate cancer (PCa) is a malignancy cause of cancer deaths and
frequently diagnosed in male. This study aimed to identify tumor suppressor genes, hub …

Association of prostate cancer with human papillomavirus infections: A case-control study

SH Yin, SD Chung, SH Hung, TC Liu… - Prostate Cancer and …, 2023 - nature.com
Background The highly oncogenic human papillomavirus (HPV) is associated with
numerous cancer types. While the role of viruses in the development of certain cancers is …