Fluorescence lifetime imaging microscopy: fundamentals and advances in instrumentation, analysis, and applications
Significance: Fluorescence lifetime imaging microscopy (FLIM) is a powerful technique to
distinguish the unique molecular environment of fluorophores. FLIM measures the time a …
distinguish the unique molecular environment of fluorophores. FLIM measures the time a …
Fluorescence lifetime techniques in medical applications
L Marcu - Annals of biomedical engineering, 2012 - Springer
This article presents an overview of time-resolved (lifetime) fluorescence techniques used in
biomedical diagnostics. In particular, we review the development of time-resolved …
biomedical diagnostics. In particular, we review the development of time-resolved …
[HTML][HTML] Optical spectroscopy for in vivo medical diagnosis—a review of the state of the art and future perspectives
When light is incident to a biological tissue surface, combinations of optical processes occur,
such as reflection, absorption, elastic and non-elastic scattering, and fluorescence. Analysis …
such as reflection, absorption, elastic and non-elastic scattering, and fluorescence. Analysis …
Multi‐wavelength fluorescence lifetime spectroscopy: a new approach to the study of endogenous fluorescence in living cells and tissues
D Chorvat Jr, A Chorvatova - Laser Physics Letters, 2009 - Wiley Online Library
The study of biological systems in their real environmental conditions is crucial to decipher
the true image of structures and processes underlying their functionality. In this regard …
the true image of structures and processes underlying their functionality. In this regard …
Fluorescence lifetime imaging distinguishes basal cell carcinoma from surrounding uninvolved skin
NP Galletly, J McGinty, C Dunsby… - British Journal of …, 2008 - academic.oup.com
Background Fluorescence lifetime imaging (FLIM) is a novel imaging technique that
generates image contrast between different states of tissue due to differences in …
generates image contrast between different states of tissue due to differences in …
Relevance of the detection of intestinal metaplasia in non-dysplastic columnar-lined oesophagus
PAC Gatenby, JR Ramus, CPJ Caygill… - Scandinavian journal …, 2008 - Taylor & Francis
Objective. In the USA, detection of intestinal metaplasia is a requirement for enrolment in
surveillance programmes for dysplasia or adenocarcinoma in columnar-lined oesophagus …
surveillance programmes for dysplasia or adenocarcinoma in columnar-lined oesophagus …
Time-domain laser-induced fluorescence spectroscopy apparatus for clinical diagnostics
We report the design and development of a compact optical fiber-based apparatus for in situ
time-resolved laser-induced fluorescence spectroscopy (tr-LIFS) of biological systems. The …
time-resolved laser-induced fluorescence spectroscopy (tr-LIFS) of biological systems. The …
Design and evaluation of a device for fast multispectral time-resolved fluorescence spectroscopy and imaging
DR Yankelevich, D Ma, J Liu, Y Sun, Y Sun… - Review of Scientific …, 2014 - pubs.aip.org
The application of time-resolved fluorescence spectroscopy (TRFS) to in vivo tissue
diagnosis requires a method for fast acquisition of fluorescence decay profiles in multiple …
diagnosis requires a method for fast acquisition of fluorescence decay profiles in multiple …
Systems for autofluorescent imaging and target ablation
ES Boyden, RA Hyde, MY Ishikawa… - US Patent …, 2012 - Google Patents
2007-11-13 Assigned to SEARETE, LLC reassignment SEARETE, LLC ASSIGNMENT OF
ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: WEAVER, THOMAS …
ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: WEAVER, THOMAS …
A randomized crossover study comparing light-induced fluorescence endoscopy with standard videoendoscopy for the detection of early neoplasia in Barrett's …
MA Kara, ME Smits, WD Rosmolen, AC Bultje… - Gastrointestinal …, 2005 - Elsevier
BACKGROUND: Light-induced fluorescence endoscopy (LIFE) may improve the detection of
high-grade dysplasia (HGD) and early stage cancer (EC) in Barrett's esophagus (BE). The …
high-grade dysplasia (HGD) and early stage cancer (EC) in Barrett's esophagus (BE). The …