Chromatin insulators: a role in nuclear organization and gene expression
J Yang, VG Corces - Advances in cancer research, 2011 - Elsevier
Chromatin insulators are DNA–protein complexes with broad functions in nuclear biology.
Based on the ability of insulator proteins to interact with each other, it was originally found …
Based on the ability of insulator proteins to interact with each other, it was originally found …
Surviving an identity crisis: a revised view of chromatin insulators in the genomics era
LH Matzat, EP Lei - Biochimica et Biophysica Acta (BBA)-Gene Regulatory …, 2014 - Elsevier
The control of complex, developmentally regulated loci and partitioning of the genome into
active and silent domains is in part accomplished through the activity of DNA-protein …
active and silent domains is in part accomplished through the activity of DNA-protein …
Convergence of topological domain boundaries, insulators, and polytene interbands revealed by high-resolution mapping of chromatin contacts in the early …
High-throughput assays of three-dimensional interactions of chromosomes have shed
considerable light on the structure of animal chromatin. Despite this progress, the precise …
considerable light on the structure of animal chromatin. Despite this progress, the precise …
Chromatin insulator factors involved in long-range DNA interactions and their role in the folding of the Drosophila genome
J Vogelmann, A Le Gall, S Dejardin, F Allemand… - PLoS …, 2014 - journals.plos.org
Chromatin insulators are genetic elements implicated in the organization of chromatin and
the regulation of transcription. In Drosophila, different insulator types were characterized by …
the regulation of transcription. In Drosophila, different insulator types were characterized by …
Genome-wide mapping of boundary element-associated factor (BEAF) binding sites in Drosophila melanogaster links BEAF to transcription
Insulator elements play a role in gene regulation that is potentially linked to nuclear
organization. Boundary element-associated factors (BEAFs) 32A and 32B associate with …
organization. Boundary element-associated factors (BEAFs) 32A and 32B associate with …
Genome organization regulates nuclear pore complex formation and promotes differentiation during Drosophila oogenesis
Genome organization can regulate gene expression and promote cell fate transitions. The
differentiation of germline stem cells (GSCs) to oocytes in Drosophila involves changes in …
differentiation of germline stem cells (GSCs) to oocytes in Drosophila involves changes in …
Regulation of the BMP Signaling-Responsive Transcriptional Network in the Drosophila Embryo
L Deignan, MT Pinheiro, C Sutcliffe, A Saunders… - PLoS …, 2016 - journals.plos.org
The BMP signaling pathway has a conserved role in dorsal-ventral axis patterning during
embryonic development. In Drosophila, graded BMP signaling is transduced by the Mad …
embryonic development. In Drosophila, graded BMP signaling is transduced by the Mad …
BEAF Regulates Cell-Cycle Genes through the Controlled Deposition of H3K9 Methylation Marks into Its Conserved Dual-Core Binding Sites
E Emberly, R Blattes, B Schuettengruber… - PLoS …, 2008 - journals.plos.org
Chromatin insulators/boundary elements share the ability to insulate a transgene from its
chromosomal context by blocking promiscuous enhancer–promoter interactions and …
chromosomal context by blocking promiscuous enhancer–promoter interactions and …
The insulator BEAF32 controls the spatial-temporal expression profile of the telomeric retrotransposon TART in the Drosophila germline
O Sokolova, V Morgunova, TV Sizova… - …, 2023 - journals.biologists.com
Insulators are architectural elements implicated in the organization of higher-order
chromatin structures and transcriptional regulation. However, it is still unknown how …
chromatin structures and transcriptional regulation. However, it is still unknown how …
Chromatin insulators: lessons from the fly
BV Gurudatta, VG Corces - Briefings in functional genomics and …, 2009 - academic.oup.com
Chromatin insulators are DNA–protein complexes with broad functions in nuclear biology.
Drosophila has at least five different types of insulators; recent results suggest that these …
Drosophila has at least five different types of insulators; recent results suggest that these …