Calixarene-based phosphinic acids as inhibitors of protein tyrosine phosphatases

VM Buldenko, VV Trush, OL Kobzar… - Bioorganic & medicinal …, 2019 - Elsevier
In the present work, the derivatives of calix [4] arene, thiacalix [4] arene, and sulfonylcalix [4]
arene bearing four methylene (phenyl) phosphinic acid groups on the upper rim of the …

[HTML][HTML] Inhibition of glutathione S-transferases by photoactive calix [4] arene α-ketophosphonic acids

O Kobzar, Y Shulha, V Buldenko, S Cherenok… - Bioorganic & Medicinal …, 2022 - Elsevier
Calix [4] arenes bearing photoactive α-ketophosphonic acid groups at the upper rim of the
macrocycle were synthesized and evaluated as inhibitors of glutathione S-transferases …

Phenylpyrazalopyrimidines as Tyrosine Kinase Inhibitors: Synthesis, Antiproliferative Activity, and Molecular Simulations

BS Chhikara, S Ashraf, S Mozaffari, N St. Jeans… - Molecules, 2020 - mdpi.com
N 1-(α, β-Alkene)-substituted phenylpyrazolopyrimidine derivatives with acetyl and
functionalized phenyl groups at α-and β-positions, respectively, were synthesized by the …

Functional calixarenes for material and life science

R Rodik, S Cherenok, O Kalchenko… - Current Organic …, 2018 - ingentaconnect.com
Calix [n] arenes–are easily accessible three-dimensional macrocyclic compounds. Modified
calix [n] arenes capable with high selectivity recognize, bind in supramolecular complexes …

Alkyl and aryl α-ketophosphonate derivatives as photoactive compounds targeting glutathione S-transferases

ОL Kobzar, YV Shulha, VM Buldenko… - … , Sulfur, and Silicon …, 2021 - Taylor & Francis
In this article, photoactive alkyl and aryl α-ketophosphonate derivatives were studied as
inhibitors of glutathione S-transferases (GSTs). The α-ketophosphonate monoesters were …

Calixarene derivatives for (nano) biotechnologies

R Roman, P Mykola, K Vitaly - Макрогетероциклы, 2017 - cyberleninka.ru
This review summarizes the author's research in the field of bio-medical application of
modified calixarenes as well as their nano-associates. The paper includes results of design …

Sulfonyl-bridged calix [4] arene as an inhibitor of protein tyrosine phosphatases

V Buldenko, O Kobzar, V Trush… - French-Ukrainian …, 2017 - kyivtoulouse.univ.kiev.ua
Previously, phosphonic acid derivatives of calix [4] arene and thiacalix [4] arene were found
to be potential inhibitors of protein tyrosine phosphatase 1B. In the present paper, the …

Inhibition of glutathione S-transferases by calix [4] arene-based phosphinic acids

OL Kobzar, YV Shulha, VM Buldenko… - Ukrainica …, 2022 - bioorganica.com.ua
Abstract Calix [4] arene-, thiacalix [4] arene-and sulfonylcalix [4] arene-based derivatives
with upper rim phosphinic acid groups were studied as inhibitors of glutathione S …

Functional calixarene nanostructures

VI Kalchenko - Theoretical and Experimental Chemistry, 2018 - Springer
The results of the author studies of functional calixarene nanostructures are summarized.
Calixarenes modified by various functional groups were created with receptor properties …

Biologically active calixarene phosphonic acids

OL Kobzar, SO Cherenok, SO Kosterin… - Ukrainica …, 2022 - bioorganica.com.ua
Phosphorylated derivatives of organic compounds are known to be capable of inhibiting the
activities of enzymes and other proteins responsible for key metabolic pathways. In this …