Syndecan-1 is a cell surface heparan sulfate proteoglycan that binds to many mediators of
disease pathogenesis. Through these molecular interactions, syndecan-1 can modulate …

Proteoglycans are a heterogeneous class of proteins bearing sulfated glycosaminoglycans.
Some of the proteoglycans have distinct core protein structures, and others display …

This review will summarize our current state of knowledge of the structure, biochemical
properties and functions of syndecans, a family of transmembrane heparan sulphate …

The syndecans are a gene family of four transmembrane heparan sulfate proteoglycans that
bind, via their HS chains, diverse components of the cellular microenvironment. To evaluate …

Many genes have been described and characterized which result in alternative
polyadenylation site use at the 3′-end of their mRNAs based on the cellular environment …

During feeding by infected mosquitoes, malaria sporozoites are injected into the host's
bloodstream and enter hepatocytes within minutes. The remarkable target cell specificity of …

Syndecans are heparan sulphate proteoglycans consisting of a type I transmembrane core
protein modified by heparan sulphate and sometimes chondroitin sulphate chains. They are …

Focal adhesion formation in fibroblasts results from complex transmembrane signaling
processes initiated by extracellular matrix molecules. Although a role for integrins with …

We have undertaken a comparative study of the interaction of the three mammalian
transforming growth factor-βs (TGF-β) with heparin and heparan sulfate. TGF-β1 and-β2, but …

Glycosylation is a common and widespread post-translational modification that affects a
large majority of proteins. Of these, a small minority, about 20, are specifically modified by …