Understanding inbreeding depression, purging, and genetic rescue

PW Hedrick, A Garcia-Dorado - Trends in ecology & evolution, 2016 - cell.com
Inbreeding depression, the reduction of fitness caused by inbreeding, is a nearly universal
phenomenon that depends on past mutation, selection, and genetic drift. Recent estimates …

Genetics in conservation management: revised recommendations for the 50/500 rules, Red List criteria and population viability analyses

R Frankham, CJA Bradshaw, BW Brook - Biological Conservation, 2014 - Elsevier
Conservation managers typically need to make prompt decisions based on limited
information and resources. Consequently, generalisations have essential roles in guiding …

Genetic rescue: A critique of the evidence supports maximizing genetic diversity rather than minimizing the introduction of putatively harmful genetic variation

K Ralls, P Sunnucks, RC Lacy, R Frankham - Biological Conservation, 2020 - Elsevier
Genetic rescue–ameliorating inbreeding depression and restoring genetic diversity of inbred
populations through gene flow-is valuable in wildlife conservation. Empirically validated …

Genetic rescue of small inbred populations: Meta‐analysis reveals large and consistent benefits of gene flow

R Frankham - Molecular ecology, 2015 - Wiley Online Library
Many species have fragmented distribution with small isolated populations suffering
inbreeding depression and/or reduced ability to evolve. Without gene flow from another …

[图书][B] Principles of animal communication

JW Bradbury, SL Vehrencamp - 1998 - learninglink.oup.com
Literature Cited to accompany Animal Communication, 2e Page 1 Principles of Animal
Communication, Second Edition Jack W. Bradbury and Sandra L. Vehrencamp Chapter 14 …

Inbreeding effects in wild populations

LF Keller, DM Waller - Trends in ecology & evolution, 2002 - cell.com
Whether inbreeding affects the demography and persistence of natural populations has
been questioned. However, new pedigree data from field populations and molecular and …

Correlation between fitness and genetic diversity

DH Reed, R Frankham - Conservation biology, 2003 - Wiley Online Library
Genetic diversity is one of the three forms of biodiversity recognized by the World
Conservation Union (IUCN) as deserving conservation. The need to conserve genetic …

Genetics and extinction

R Frankham - Biological conservation, 2005 - Elsevier
The role of genetic factors in extinction has been a controversial issue, especially since
Lande's paper [Genetics and demography in biological conservation, Science 241 (1988) …

Most species are not driven to extinction before genetic factors impact them

D Spielman, BW Brook… - Proceedings of the …, 2004 - National Acad Sciences
There is controversy concerning the role of genetic factors in species extinctions. Many
authors have asserted that species are usually driven to extinction before genetic factors …

Purging of strongly deleterious mutations explains long-term persistence and absence of inbreeding depression in island foxes

JA Robinson, C Brown, BY Kim, KE Lohmueller… - Current Biology, 2018 - cell.com
The recovery and persistence of rare and endangered species are often threatened by
genetic factors, such as the accumulation of deleterious mutations, loss of adaptive potential …