Brain organoids: advances, applications and challenges
Brain organoids are self-assembled three-dimensional aggregates generated from
pluripotent stem cells with cell types and cytoarchitectures that resemble the embryonic …
pluripotent stem cells with cell types and cytoarchitectures that resemble the embryonic …
Deconstructing cortical folding: genetic, cellular and mechanical determinants
C Llinares-Benadero, V Borrell - Nature Reviews Neuroscience, 2019 - nature.com
Folding of the cerebral cortex is a fundamental milestone of mammalian brain evolution and
is associated with dramatic increases in size and complexity. New animal models, genetic …
is associated with dramatic increases in size and complexity. New animal models, genetic …
Cerebral cortex expansion and folding: what have we learned?
V Fernández, C Llinares‐Benadero, V Borrell - The EMBO journal, 2016 - embopress.org
One of the most prominent features of the human brain is the fabulous size of the cerebral
cortex and its intricate folding. Cortical folding takes place during embryonic development …
cortex and its intricate folding. Cortical folding takes place during embryonic development …
[HTML][HTML] New insights into the dynamic development of the cerebral cortex in childhood and adolescence: Integrating macro-and microstructural MRI findings
Through dynamic transactional processes between genetic and environmental factors,
childhood and adolescence involve reorganization and optimization of the cerebral cortex …
childhood and adolescence involve reorganization and optimization of the cerebral cortex …
How cells fold the cerebral cortex
V Borrell - Journal of Neuroscience, 2018 - Soc Neuroscience
Folding of the cerebral cortex is as highly intriguing as poorly understood. At first sight, this
may appear as simple tissue crumpling inside an excessively small cranium, but the process …
may appear as simple tissue crumpling inside an excessively small cranium, but the process …
Evolution of neocortical folding: A phylogenetic comparative analysis of MRI from 34 primate species
We conducted a comparative analysis of primate cerebral size and neocortical folding using
magnetic resonance imaging data from 65 individuals belonging to 34 different species. We …
magnetic resonance imaging data from 65 individuals belonging to 34 different species. We …
White matter volume and white/gray matter ratio in mammalian species as a consequence of the universal scaling of cortical folding
B Mota, SE Dos Santos… - Proceedings of the …, 2019 - National Acad Sciences
Because the white matter of the cerebral cortex contains axons that connect distant neurons
in the cortical gray matter, the relationship between the volumes of the 2 cortical …
in the cortical gray matter, the relationship between the volumes of the 2 cortical …
Structural covariance networks in schizophrenia: A systematic review Part II
Background Examination of structural covariance network (SCN) is gaining prominence
among the strategies to delineate dysconnectivity that case-control morphometric …
among the strategies to delineate dysconnectivity that case-control morphometric …
Genetic maps and patterns of cerebral cortex folding
C de Juan Romero, V Borrell - Current opinion in cell biology, 2017 - Elsevier
Folding of the cerebral cortex during brain development is a complex process that depends
on the orchestrated action of a number of factors, including generation and proliferation of …
on the orchestrated action of a number of factors, including generation and proliferation of …
Universality in human cortical folding in health and disease
The folding of the cortex in mammalian brains across species has recently been shown to
follow a universal scaling law that can be derived from a simple physics model. However, it …
follow a universal scaling law that can be derived from a simple physics model. However, it …