Polymeric delivery of therapeutic nucleic acids

R Kumar, CF Santa Chalarca, MR Bockman… - Chemical …, 2021 - ACS Publications
The advent of genome editing has transformed the therapeutic landscape for several
debilitating diseases, and the clinical outlook for gene therapeutics has never been more …

Bottlebrush polymers: From controlled synthesis, self-assembly, properties to applications

Z Li, M Tang, S Liang, M Zhang, GM Biesold… - Progress in Polymer …, 2021 - Elsevier
Bottlebrush polymers (BBPs) have emerged as intriguing class of materials for an array of
applications, including supersoft elastomers, organic optoelectronics, templates for crafting …

Click chemistry strategies for the accelerated synthesis of functional macromolecules

Z Geng, JJ Shin, Y Xi, CJ Hawker - Journal of Polymer Science, 2021 - Wiley Online Library
Click chemistry is one of the most powerful strategies for constructing polymeric soft
materials with precise control over architecture and functionality. In this review, we provide a …

50th Anniversary Perspective: Polymer Functionalization

E Blasco, MB Sims, AS Goldmann, BS Sumerlin… - …, 2017 - ACS Publications
The translation of small molecule chemistries into efficient methodologies for polymer
functionalization spans several decades, enabling critical advances in soft matter materials …

Antiviral polymers: past approaches and future possibilities

RH Bianculli, JD Mase, MD Schulz - Macromolecules, 2020 - ACS Publications
Treating a viral disease is no simple feat. Drug resistance, latent reservoirs in the body,
emerging novel viruses, and a frequent lack of specific treatments all complicate antiviral …

Heterogeneous graphitic carbon nitrides in visible-light-initiated organic transformations

SK Verma, R Verma, YR Girish, F Xue, L Yan… - Green …, 2022 - pubs.rsc.org
In recent years, g-C3N4 photocatalyst-mediated organic reactions have represented an
important mode of chemical transformations and are expected to become a crucial field at …

Functional biodegradable polymers via ring-opening polymerization of monomers without protective groups

G Becker, FR Wurm - Chemical society reviews, 2018 - pubs.rsc.org
Biodegradable polymers are of current interest and chemical functionality in such materials
is often demanded in advanced biomedical applications. Functional groups often are not …

Amphiphilic AIEgen‐polymer aggregates: Design, self‐assembly and biomedical applications

S Cao, J Shao, LKEA Abdelmohsen… - Aggregate, 2022 - Wiley Online Library
Aggregation‐induced emission (AIE) is a phenomenon in which fluorescence is enhanced
rather than quenched upon molecular assembly. AIE fluorogens (AIEgens) are flexible …

Palladium-catalyzed Suzuki–Miyaura coupling of aryl esters

T Ben Halima, W Zhang, I Yalaoui, X Hong… - Journal of the …, 2017 - ACS Publications
The Suzuki–Miyaura coupling is among the most important C–C bond-forming reactions
available due to its reliability, chemoselectivity, and diversity. Aryl halides and …

Advances in polymerizations modulated by external stimuli

AM Doerr, JM Burroughs, SR Gitter, X Yang… - ACS …, 2020 - ACS Publications
Synthetic polymer chemistry endeavors to imitate the spatial and temporal control exhibited
within biological systems to obtain well-defined polymeric materials with unique structures …