Recent advances in functional nanomaterials for light–triggered cancer therapy
Photo–triggered therapeutic modalities for cancer have attracted enormous attention in
recent years due to the easily focused and tuned properties of irradiation light that enable …
recent years due to the easily focused and tuned properties of irradiation light that enable …
Hypoxia-targeted drug delivery
Hypoxia is a state of low oxygen tension found in numerous solid tumours. It is typically
associated with abnormal vasculature, which results in a reduced supply of oxygen and …
associated with abnormal vasculature, which results in a reduced supply of oxygen and …
Fluorescent chemical probes for accurate tumor diagnosis and targeting therapy
Surgical resection of solid tumors is currently the gold standard and preferred therapeutic
strategy for cancer. Chemotherapy drugs also make a significant contribution by inhibiting …
strategy for cancer. Chemotherapy drugs also make a significant contribution by inhibiting …
Cancer‐associated, stimuli‐driven, turn on theranostics for multimodality imaging and therapy
Advances in bioinformatics, genomics, proteomics, and metabolomics have facilitated the
development of novel anticancer agents that have decreased side effects and increased …
development of novel anticancer agents that have decreased side effects and increased …
Tumor‐targeting glycol chitosan nanoparticles for cancer heterogeneity
Nanomedicine is extensively employed for cancer treatment owing to its unique advantages
over conventional drugs and imaging agents. This increased attention to nanomedicine …
over conventional drugs and imaging agents. This increased attention to nanomedicine …
Intraligand excited states turn a ruthenium oligothiophene complex into a light-triggered Ubertoxin with anticancer effects in extreme hypoxia
Ru (II) complexes that undergo photosubstitution reactions from triplet metal-centered (3MC)
excited states are of interest in photochemotherapy (PCT) due to their potential to produce …
excited states are of interest in photochemotherapy (PCT) due to their potential to produce …
Fluorogenic reaction-based prodrug conjugates as targeted cancer theranostics
Theranostic systems are receiving ever-increasing attention due to their potential
therapeutic utility, imaging enhancement capability, and promise for advancing the field of …
therapeutic utility, imaging enhancement capability, and promise for advancing the field of …
[HTML][HTML] Recent advances in self-immolative linkers and their applications in polymeric reporting systems
AG Gavriel, MR Sambrook, AT Russell, W Hayes - Polymer Chemistry, 2022 - pubs.rsc.org
Interest in self-immolative chemistry has grown over the past decade with more research
groups harnessing the versatility to control the release of a compound from a larger …
groups harnessing the versatility to control the release of a compound from a larger …
[HTML][HTML] Breaking the barrier: an osmium photosensitizer with unprecedented hypoxic phototoxicity for real world photodynamic therapy
Hypoxia presents a two-fold challenge in the treatment of cancer, as low oxygen conditions
induce biological changes that make malignant tissues simultaneously more aggressive and …
induce biological changes that make malignant tissues simultaneously more aggressive and …
Innovative linker strategies for tumor‐targeted drug conjugates
A Dal Corso, L Pignataro, L Belvisi… - … –A European Journal, 2019 - Wiley Online Library
The covalent conjugation of potent cytotoxic agents to either macromolecular carriers or
small molecules represents a well‐known approach to increase the therapeutic index of …
small molecules represents a well‐known approach to increase the therapeutic index of …