Epithelial-to-mesenchymal transition (EMT) and its reversed process, mesenchymal-to-
epithelial transition (MET), are fundamental processes in embryonic development and tissue …

Epithelial–mesenchymal transition (EMT) is a developmental process whereby stationary,
adherent cells acquire the ability to migrate. EMT is critical for dramatic cellular movements …

Abstract Since 1992, FlyBase (flybase. org) has been an essential online resource for the
Drosophila research community. Concentrating on the most extensively studied species …

The significant parallels between cell plasticity during embryonic development and
carcinoma progression have helped us understand the importance of the epithelial …

Recent interest in the control of bone metabolism has focused on a specialized subset of
CD31hiendomucinhi vessels, which are reported to couple angiogenesis with osteogenesis …

Morphogenesis of an organism requires the development of its parts to be coordinated in
time and space. While past studies concentrated on defined cell populations, a synthetic …

Snail is primarily known as a transcriptional repressor that induces epithelial-mesenchymal
transition by suppressing adherent proteins. Emerging evidence suggests that Snail can act …

A major challenge in biology is to understand how complex gene expression patterns are
encoded in the genome. While transcriptional enhancers have been studied extensively, few …

Melanoma is an aggressive form of skin cancer due to its high metastatic abilities and
resistance to therapies. Melanoma cells reside in a heterogeneous tumour …

The zinc finger protein Snail is a master regulator of epithelial–mesenchymal transition
(EMT) and a strong inducer of tumor metastasis, yet the signal cascades triggered by Snail …