Spray-drying is an inherently continuous and well-established industrial drying process. It
can accelerate manufacturing of biopharmaceuticals and vaccine products, resulting in both …

Liquid formulations of vaccines are subject to instabilities that result from degradation
processes that proceed via a variety of physical and chemical pathways. In dried …

Introduction Vaccines represent he most common and safer ways of combating infectious
diseases. Loss of potency owing to thermal denaturation or degradation of almost all the …

Human papillomaviruses (HPVs) are the most common sexually transmitted infections
worldwide. Ninety percent of infected individuals clear the infection within two years; …

Vaccines are a very important tool in the effort to reduce the global burden of infectious
diseases. Modern vaccines can be formulated in several ways to induce specific immunity …

Vaccines not requiring cold-chain storage/distribution and suitable for needle-free delivery
are urgently needed. Pulmonary administration is one of the most promising non-parenteral …

Oral papilloma lesions may appear as a result of HPV infection, or not, and only special
molecular methods could differentiate them. Low-risk and high-risk HPV types could induce …

Dry powder inhalation formulations have become increasingly popular for local and
systemic delivery of small molecules and biotherapeutics. Powder formulations provide …

Thermostability and decreased component costs are desirable features for adjuvanted,
recombinant vaccines. We previously showed that a model malaria transmission-blocking …

Converting a vaccine into a thermostable dry powder is advantageous as it reduces the
resource burden linked with the cold chain and provides flexibility in dosage and …