Water‐mediated interactions destabilize proteins

T Sumi, H Imamura - Protein Science, 2021 - Wiley Online Library
Proteins are folded to avoid exposure of the nonpolar groups to water because water‐
mediated interactions between nonpolar groups are a promising factor in the …

Unveiling the interaction potential surface between drug-entrapped polymeric micelles clarifying the high drug nanocarrier efficiency

T Morita, S Mukaide, Z Chen, K Higashi, H Imamura… - Nano …, 2021 - ACS Publications
Polymeric micelles are invaluable media as drug nanocarriers. Although knowledge of an
interaction between the micelles is a key to understanding the mechanisms and developing …

Pair Potential between Poloxamer 407 Micelles in 14 wt% Aqueous Solution Clarifying the Sol–Gel–Sol Transition by Temperature Rise

T Morita, Y Torii, H Imamura, T Kadota… - The Journal of …, 2024 - ACS Publications
Poloxamer 407 (P407) is used as a safety-guaranteed, invaluable pharmaceutical
nanocarrier. The aqueous solution of P407 exhibits sol-to-gel and gel-to-sol transitions …

Interaction potential between biological sensing nanoparticles determined by combining small-angle x-ray scattering and model-potential-free liquid theory

T Morita, N Uehara, K Kuwahata… - The Journal of …, 2016 - ACS Publications
Biological sensing technology utilizing nanoparticles extends through a diverse range of
fields. The nanosensing is controlled using the assembly/disassembly of nanoparticles …

An improved model-potential-free analysis of the structure factor obtained from a small-angle scattering: acquisitions of the pair distribution function and the pair …

K Amano, R Sawazumi, H Imamura, T Sumi… - Chemistry …, 2020 - academic.oup.com
Small-angle X-ray and neutron scatterings can measure the structure factor of dispersed
particles (macromolecules or colloidal particles), which can estimate the pair distribution …

Packing and dynamics of a protein solution approaching the jammed state

N Begam, S Da Vela, O Matsarskaia, MK Braun… - Soft Matter, 2020 - pubs.rsc.org
The packing of proteins and their collective behavior in crowded media is crucial for the
understanding of biological processes. Here we study the structural and dynamical evolution …

Free-Energy Functional Approach to Inverse Problems for Self-Assembly of Three-Dimensional Crystals

M Torikai - Journal of the Physical Society of Japan, 2021 - journals.jps.jp
In this study, a variational method for the inverse problem of self-assembly, ie, a
reconstruction of the interparticle interaction potential of a given structure, is applied to three …

Interaction potential surface between Raman scattering enhancing nanoparticles conjugated with a functional copolymer

T Morita, Y Ogawa, H Imamura, K Ookubo… - Physical Chemistry …, 2019 - pubs.rsc.org
A novel Raman scattering enhancement was discovered using colloid nanoparticles
conjugated with an amine-based copolymer. The interaction potential surface between …

[PDF][PDF] The structure factor of myoglobin determined by using the experimental and the calculated form factor

H Imamura, T Sumi, H Ohgi, Y Isogai - pfwww.kek.jp
2 Experiments The SAXS experiments were performed at the beamline BL-10C. The X-ray
wavelength was 0.1488 nm; the camera length was 1048 mm, which was calibrated by use …

[PDF][PDF] Model-potential-free analysis of an inter-particle interference of protein solution scattering: insights into solvent effects on the intermolecular interaction

H Imamura, T Sumi, H Ohgi, Y Isogai - pfwww.kek.jp
2 Experiments The SAXS experiments were performed at the beam line BL-10C. The X-ray
wavelength was 0.1488 nm; the camera length was 957 or 1048 mm, which was calibrated …